Biochemistry

An interdepartmental B.S. biochemistry major is offered in the College of Arts and Sciences. The B.S. in biochemistry degree is managed by an interdepartmental committee composed of biochemists, bioorganic chemists, and molecular/cellular biologists. The committee administers the degree, monitors the academic program, provides research possibilities, and advises student majors. The director of the program is currently Linda J. Lowe-Krentz. Faculty in both Biological Sciences (Lowe-Krentz and Iovine) and Chemistry (Schray) serve as advisors. Majors should be declared in Biological Sciences.

Bachelor of Science Degree inBiochemistry

I. College and University Requirements (25)

a.

ENGL 1, 2 (6)

b.

First Year Seminar (3)

c.

Nonscience electives: 16 hours to be broadly distributed in fields of thought other than natural science and mathematics, including at least 8 hours each in humanities and social sciences.

II. Collateral Science Requirements (at least 24)

a.

Physics 10, 12, 13, 22 (or 11, 12, 21, 22) (9 or 10)

b.

Mathematics 51, 52, 43 (or 21, 22, 23) and a statistics course (at least 12)

c.

Survey of Computer Science 12 or Engineering 1 (3)

III. Required Chemistry Courses (25)

a.

Introductory Chemistry 40, 41 (8*)

b.

Organic Chemistry 110, 111, 112, 113 (8)

c.

Inorganic Chemistry 307 (3)

d.

Physical Chemistry 194 (3)

e.

Analytical Chemistry 332 (3)

*The Chemistry 30/31 sequence may be substituted.

IV. Required Biological Science courses (25 minimum)

a.

Biology Core I: Cellular and Molecular and Laboratory 41, 42 (4)

b.

Biology Core II: Genetics 115 (3)

c.

Biochemistry 371, 372, 377 (9)

d.

Advanced Laboratory (4)

e.

Electives in Biological Sciences (3 hours minimum*)

f.

Technical Writing (2 hours minimum)

*The three credit hours of biological sciences electives are chosen with the approval of the adviser.

Model Pattern Roster

Freshman year

CHM 40, 41 Concepts, Models, and Experiments I and II (8)
BIOS 41, 42 Biology Core I: Cell and Molecular and Laboratory (4)
MATH 51, 52 orSurvey of Calculus I and II (7)
MATH 21, 22 Calculus I and II (8)
Dept 90 College Seminar (3)
ENGL 1,2 Composition and Literature (6)
PHY 10, 12 or General Physics I and Laboratory (5)
PHY 11, 12 Introductory Physics I and Laboratory (5)

Sophomore year

CHM 110, 111, 112, 113 Organic Chemistry and Laboratory (8)
PHY 13, 22 or General Physics II and Laboratory (4)
PHY 21, 22 Introductory Phys. II and Laboratory MATH 43 or Linear Algebra (3)
MATH 23 Calculus III
BIOS 130 Biostatistics*
BIOS 115 Biology Core II: Genetics

*A statistics course from the MATH department could also fulfill the statistics requirement

Junior year

CHM 194 Physical Chemistry for Biological Sciences (3)
CHM 332 Analytical Chemistry (3)
BIOS 371, 372 Elem. of Biochemistry I and II (6)
BIOS 377 Biochem. Lab (3)
CSE 12 Survey of Computer Science (3)
Technical Writing (2)

Senior year

BIOS Advanced laboratory course(s)
BIOS elective
CHM 307 Advanced Inorganic Chemistry (3)

Bioengineering Program

Professor Anand Jagota, Director, Department of Chemical Engineering at 610-758-4396 or anj6@lehigh.edu

Professor H.D. OuYang, Associate Director, Department of Physics at 610-758-3920 or hdo0@lehigh.edu

Program Associated Professors: Derick Brown, Ph.D. (Princeton) Civil and Environmental Engineering; Xuanhong Cheng, Ph.D. (U. of Washington) Materials Science and Engineering; James T. Hsu, Ph.D. (Northwestern) Chemical Engineering; Sabrina Jedlicka Ph.D. (Purdue) Materials Science and Engineering; Ian Laurenzi, Ph.D. (University of Pennsylvania) Chemical Engineering; Mary Kathryn Iovine, Ph.D. (Washington, St. Louis) Biological Sciences; Anand Jagota, Ph.D. (Cornell) Chemical Engineering; Himanshu Jain, Eng.Sc.D. (Columbia), Materials Science and Engineering; Daniel Lopresti, Ph.D. (Princeton) Computer Science; Linda LoweKrentz, Ph.D. (Northwestern) Biological Sciences; A.J. McHugh, Ph.D. (Delaware) Chemical Engineering; Wojciech Z. Misiolek, Ph.D. (Poland) Materials Science and Engineering; John Ochs, Ph.D. (Pennsylvania State) Mechanical Engineering and Mechanics; BoonSiew Ooi, Ph.D. (Glasgow, United Kingdom) Electrical and Computer Engineering; H. Daniel OuYang, Ph.D. (UCLA) Physics; Eric P. Salathe, Ph.D., (Brown) Mathematics; Neal G. Simon, Ph.D. (Rutgers) Biological Sciences; Svetlana TaticLucic, Ph.D. (California Institute of Technology) Electrical and Computer Engineering; Arkady S. Voloshin, Ph.D. (TelAviv University, Israel), Mechanical Engineering and Mechanics Professor of Practice: Lori E. Herz, Ph.D. (Rutgers) Chemical Engineering; R. Sam Niedbala, Ph.D. (Lehigh University) Chemistry; Susan F. Perry, Ph.D. (Pennsylvania State University) Chemical Engineering

The mission of the Bioengineering Program is to prepare undergraduate students to be critical thinkers, problem solvers, innovators, leaders, and lifelong learners who can make a positive impact at the interfaces among the physical and life sciences, and engineering.

To achieve its educational mission, the Bioengineering Program has established the following set of Program Educational Objectives. Three to five years after graduation, we expect our students will:

1. formulate and synthesize innovative solutions to biomedical and biotechnology problems using modern engineering methodologies;
2. incorporate physical and life sciences, and mathematics as part of their problem solving processes;
3. contribute and function well in the collaborative and interdisciplinary environments required to solve complex biomedical and biotechnology problems;
4. incorporate contemporary and ethical issues in the solution of bioengineering problems;
5. communicate effectively in both oral and written forms;
6. engage in lifelong learning processes during their professional careers.

The B.S. in Bioengineering degree provides a structured curriculum comprised of three tracks. Biopharmaceutical Engineering is for students whose interests lie in genomics, proteomics, bioinformatics, recombinant DNA, protein engineering, bioprocessing, drug synthesis and delivery. The Bioelectronics/photonics track covers education and research dealing with signal processing, biosensors, MEMs, biochips for DNA sequencing, laser and fiber based optical technology for biomedical applications. Cell and Tissue Engineering encompasses biomaterials and biomechanics, from cells and tissue to organs and systems.

The B.S. in Bioengineering will prepare students for careers in established and emerging fields that require combining engineering principles with the life sciences. Potential paths open to students include the health care, biomedical, pharmaceutical, biomaterials, and other biotechnologyrelated industries through careers in medicine or graduate studies.

The program strongly encourages experiential learning, including two summers of internships, required participation in Lehigh's Integrated Product Development (IPD) program, and opportunities for undergraduate research for credit.

Requirement of the major 132 credit hours are required for graduation with a degree of bachelor of science in bioengineering.

Bioengineering Core Requirements

General Requirements (23 credits)

Engl 1 Composition and Literature (3)
Engl 2 Composition and literature: Fiction, Drama, Poetry (3)
Phil 116 Bioethics (4) Engr 1 Engineering Computations (3)
Eco 1 Principles of Economics (4)
Sufficient electives to satisfy HSS requirements
Free Electives (10)

Mathematics (18 credits)

Chemistry (12 credits)

Chem 30 Intro. Chemical Principles and Laboratory (4)
Chem 31 Chemical Equilibria in Aqueous Systems (4)
Chem 110, 111 Organic Chemistry I and Lab (4)
Physics (10 credits)
Physics 11,12 Intro. Physics I and Lab (5)
Physics 21,22 Intro. Physics II and Lab (5)
Biological Sciences (8 credits)
BioS 41 and 42 Biology Core I: Cellular and Molecular and Lab (4)
BioS 115/116 Biology Core II: Genetics and Lab (4)

Integrated Bioengineering (16 credits)

Required by all Three Tracks

BioE 01 Freshman Seminar I, Introduction to Bioengineering I: Philosophy to Practice (Pass/Fail) (1)
BioE 02 Freshman Seminar 2, Introduction to Bioengineering II: Current Topics (Pass/Fail) (1)
BioE 110 Elements of Bioengineering (4)
BioE 210 Bioengineering Physiology (4)
Engr 211 Integrated Product Development I (IPD) (3)
Engr 212 Integrated Product Development II (IPD) (2)
BioE 225 cGMP Good manufacturing practice and regulatory affairs for bioengineers (1)

Engineering Requirement by Track

Biopharmaceutical Engineering Track (23 credits)

Chem 112 Organic Chemistry II (3)
BioE 343 Integrated Biotechnology Laboratory (3)
Mat 33 Engineering Materials and Processes (3)
ChE 31 Material and Energy Balance (3)
ChE 210 Chemical Engineering Thermodynamics (4)
ChE 211 Chemical Reactor Design (3)*
ChE 44 Fluid Mechanics (4)

*Note: ChE 344 (Molecular Bioengineering) or BioE/ChE 397 (Metabolic Engineering) may be taken in lieu of ChE 211.

Bioelectronic/Biophotonics Track (22 credits)

ECE 108 Signals and Systems (4)
BioE 331 Integrated Bioelectronics/Photonics Laboratory (2)
ECE 81 Principles of Electrical Engineering (4)
ECE 123 Electronic Circuits (3) or Phy 190 Electronics (3)
ECE 202 Introduction to Electromagnetics (3) or Phy 212 Electricity and Magnetism I (3)
Mech 3 Elementary Engineering Mechanics (3)
Mat 33 Engineering Materials and Processes (3)

Cell and Tissue Engineering Track (21 credits)

BioE 120,121 Biomechanics and Laboratory (4)
BioE 357 Biostructural Mechanics Laboratory (2)
Mech 3 Elementary Engineering Mechanics (3)
Mech 12 Strength of Materials (3)
Mat 33 Engineering Materials and Processes (3)
ME 104 Thermodynamics (3) or Phy 340 Thermal Physics (3)
ME 231 Fluid Mechanics (3)

Bioengineering Electives

Students must take three (3) credits from the following:

ChE 341 Biotechnology I (3)
ChE 344 Molecular Bioengineering (3)
BioE 321 (Phy 321) Biomolecular & Cellular
Mechanics (3)
BioE 335 BioFluid Mechanics of Physiological Systems (3)

Students must take nine (9) credits from approved electives; no more than six (6) can be from BioE 132, BioE 142, BioE 242, and BioE 290.

Approved electives: BioE 132, BioE 142, BioE 242, BioE 290, BioE 321, BioE 335, BioE 324, BioE 350, BioS 177, BioS 345346, BioS 367, BioS 371, BioS 277, ChE 341, ChE 342, ChE 343, ChE 344, ChE 388, ChE 391, Chm 332, CSE 408, ECE 202, ECE 333, Phy 212, Phy 352. Other upper level classes may also qualify.

Typical four-year course schedule for BS in Bioengineering

Freshman year, first semester (same for all three tracks) (14 credits)

BioE 1 Freshman Seminar (1) (Pass/Fail)
Chm 30 Introductory Chemical Principles and lab (4)
Math 21 Calculus I (4) Engr 1 Engineering Computations (3)
English 1 Composition and Literature (3)

Freshman year, second semester (same for the three tracks) (15 credits)

BioE 2 Freshman Seminar 2 (1) (Pass/Fail)
BioS 41/42 Biology Core I: Cellular and Molecular and Lab (4)
Math 22 Calculus II (4)
Phy 11/12 Introductory Physics I and Lab (5)
Engl 2 Composition and Literature II (3)

Biopharmaceutical Engineering Track

Sophomore year first semester (18 credits)

BioE 110 Elements of Bioengineering (4)
Mat 33 Engineering Materials and Processing (3)
Math 23 Calculus III (4) ChE 31 Material and Energy Balances of Chemical Processes (3)
Eco 1 Principles of Economics (4)

Sophomore year second semester (16) credits)

BioE 210 Introduction to Engineering Physiology (4)
Chm 31 Chemical Equilibria in Aqueous Systems (4)
Phy 21/22 Introductory Physics II and Lab (5)
ChE 210 Chemical Engineering Thermodynamics (4)

Junior year, first semester (17 credits)

Math 205 Linear Methods (3)
Chm 110, 111 Organic Chemistry I and Lab (4)
BioS 115/116 Biology Core II: Genetics and Lab (4)
ChE 341 Biotechnology I (3)
Elective (3)

Junior year, second semester (16 credits)

Math 231 Probability and Statistics (3)
ENG 211 Integrated Product Development I (3)
ChE 44 Fluid Mechanics (4)
ChE 211 Chemical Reactor Design (3)
Chm 112 Organic Chemistry II (3)

Senior year, first semester (16 credits)

ENG 212 Integrated Product Development II (2)
BIOE 225 cGMP Good manufacturing practice and regulatory affairs for bioengineers (1)
BioE 343 Integrated Biotechnology Laboratory (3)
Electives (10)

Senior year, second semester (15) credits

Phil 116 Bioethics (4)
Electives (11)

Bioelectronics/Biophotonics Track

Sophomore year, first semester (17 credits)

BioE 110 Elements of Bioengineering (4)
Math 23 Calculus II (4)
ECE 81 Principles of Electrical Engineering (4)
Phy 21/22 Introductory Physics II and Lab (5)

Sophomore year, second semester (18 credits)

BioE 210 Introduction to Engineering Physiology (4)
Math 205 Linear Methods (3)
Mech 3 Fundamentals of Engineering Mechanics (3)
Chm 31 Chemical Equilibria of Aqueous Systems (4)
ECE 121/123 Electronic Circuits and Lab (5)

Junior year, first semester (16 credits)

BioS 115/116 Biology Core II: Genetics and Lab (4)
Chm 110, 111 Organic Chemistry I and Lab (4)
Mat 33 Engineering Materials and Processes (3)
ECE 108 Signals and Systems (4)

Junior year, second semester (15 credits)

Math 231 Probability and Statistics (3)
ENG 211 Integrated Product Development I (3)
BioE 331 Integrated Bioelectronics/Photonics Laboratory (2)
Eco 1 Principles of Economics (4)
Elective (3)

Senior year, first semester 16 credits)

ENG 212 Integrated Product Development II (2)
BioE 225 cGMP Good manufacturing practice and regulatory affairs for bioengineers (1)
ECE 202 Introduction to Electromagnetics (3) or Phy 212 Electricity and Magnetism I (3)
Electives (10)

Senior year, second semester (15 credits)

Phil 116 Bioethics (4)
Electives (11)

Cell and Tissue Engineering Track

Sophomore year, first semester (16 credits)

BioE 110 Elements of Bioengineering (4)
Mech 3 Engineering Materials and Processes (3)
Math 23 Calculus III (4)
Phy 21/22 Introductory Physics II and Lab (5)

Sophomore year, second semester (17 credits)

BioE 210 Introduction to Engineering Physiology (4)
Math 205 Linear Methods (3)
Chm 31 Chemical Equilibria in Aqueous Systems (4)
Mech 12 Strengths of Materials (3)
Mat 33 Engineering Materials and Processes (3)

Junior year, first semester (17 credits)

BioE 120/121 Biomechanics and Biomechanics Laboratory (4)
Chm 110, 111 Organic Chemistry I and Lab (4)
BioE 357 Integrated Biostructural Mechanics Laboratory (2)
BioS 115/116 Biology Core II: Genetics and Lab (4)
Elective (3)

Junior year, second semester (16 credits)

Math 231 Probability and Statistics (3)
ENG 211 Integrated Product Development I (3)
ME 104 Thermodynamics I (3)
Eco 1 Principles of Economics (4)
Electives (3)

Senior year, first semester (16 credits)

ENG 212 Integrated Product Development II (2)
BioE 225 cGMP Good manufacturing practice and regulatory affairs for bioengineers (1)
ME 231 Thermodynamics I (3)
Electives (10)

Senior year, second semester (15)

Phil 116 Bioethics (4)
Electives (11)

BioE 1. Freshman Seminar 1, Introduction to Bioengineering 1: Philosophy to Practice (1) fall

Overview of the bioengineering field, the advancements of related topics in sciences, technology, engineering and applications for health care and medicine. Humanity and ethical issues. Pass/Fail

BioE 2. Freshman Seminar 2, Introduction to Bioengineering II: Current Topics spring (1)

Overview of a broad spectrum of current topical areas in biotechnology and bioengineering and their applications in health care and medicine. Pass/Fail

BioE 10. Bioengineering Sophomore Seminar I: Literature Research (1) fall

Literature research on current bioengineering and biotechnology topics to assemble information for producing a written research proposal.

BioE 20. Bioengineering Sophomore Seminar II: Research Proposal (1) spring

Prepare written research proposals for research projects. Define research topics, objectives of the research, specific goals, methodology, research plans and expected impact of the research.

BioE 110. Elements of Bioengineering (4) fall

An introduction to the fields of biotechnology and biomedical engineering. The areas include biomechanics, biomaterials, bioinstrumentation, medical imaging, rehabilitation engineering, biosensors, biotechnology and tissue engineering. Prerequisites BioS 41 and 42.

BioE 120/121Biomechanics and Biomechanics Laboratory (3/1) fall

Applications of mechanics to study behavior of anatomical structures and biological tissues of the musculoskeletal system. Specific topics include structure and function of biological tissues, mechanical properties of biological tissues, and analysis of specific tissues (i.e. bone, muscle, and soft connective tissues) Coprerequisite MECH 3.

BioE 132. Bioengineering Research 1 (2) fall

Research on a topic chosen by students, with the help of a faculty advisor from among the three bioengineering tracks (biopharmaceutical engineering, bioelectronic/biophotonics or cell and tissue engineering). Independent meetings with advising professor will track progress. Includes written report and oral presentation. Prerequisite junior standing and permission of instructor.

BioE 142 Bioengineering Research 2 (2) spring

Continuation of research initiated in BioE 132, Research 1. Topic chosen by student, with the help of a faculty advisor from among the three bioengineering tracks (biopharmaceutical engineering, bioelectronic/biophotonics or cell and tissue engineering). Independent meetings with advising professor will track progress. Includes written report and oral presentation. Prerequisite BioE 132 or permission of instructor.

BioE 210. Introduction to Engineering Physiology (4) spring

Mammalian physiology for bioengineering students, with an emphasis on control mechanisms and engineering principles. Basic cell function; biological control systems; muscle; neural; endocrine, circulatory, digestive, respiratory, renal, and reproductive systems; regulation of metabolism and defense mechanisms. Includes laboratory work. Prerequisite BioE 110, BioS 41 and 42.

BioE 225. GMP Good manufacturing practice and regulatory affairs for bioengineers (1) fall

Review of the principles of the Food and Drug Administration including its history, mission and applied regulations. Understanding of how the FDA works with industry and is integral to the development of new products and technologies. Review and critique of case studies in various parts of the biomedical industry to see how FDA regulations are applied. Validation and analysis of products using failure mode analysis.

BioE 242. Bioengineering Research 3 (2) fall

Continuation of research initiated in BioE 132 and 142. Topic chosen by student, with a faculty advisor from among the three bioengineering tracks (biopharmaceutical engineering, bioelectronic/biophotonics or cell and tissue engineering). Written and oral reports approved by research advising professor will track progress. Prerequisite BioE 142 or permission of instructor.

BioE 290 Bioengineering Thesis (13) spring

Thesis, guided by a faculty advisor, based on work conducted in BioE 132, 142, 242, or in ENG 211, 212. Includes written report and oral presentation. Prerequisite BioE 242 or ENG 212 or permission of instructor.

BioE 331 Integrated Bioelectronics/Biophotonics Laboratory (2) spring

Experiments in design and analysis of bioelectronics circuits, micropattering of biological cells, micromanipulation of biological cells using electric fields, analysis of pacemakers, instrumentation and computer interfaces, ultrasound, optic, laser tweezers and advanced imaging and optical microscopy techniques for biological applications, Prerequisites Phy 13/22 or Phy 21/22 and ECE 81 or Phy 190, or permission of instructor.

BioE 321 (Phy 321) Biomolecular & Cellular Mechanics (3)

Mechanics and physics of the components of the cell, ranging in length scale from fundamental biomolecules to the entire cell. The course covers the mechanics of proteins and other biopolymers in 1D, 2D, and 3D structures, cell membrane structure and dynamics, and the mechanics of the whole cell. Prerequisites Math 205, Math 231, and Phy 13/22 or 21/22, or permission of the instructor.

BioE 324 (MAT 324) Introduction to Organic Biomaterials (3) spring

Overview of the field of biomaterials, covering basic concepts in biomaterials, biological response and biomaterial applications.

BioE 325 (MAT 325) Inorganic Biomaterials (3) Fall

Fabrication methods for biomedical implants and devices. Selection of metals and ceramics with specific bulk and surface physical as well as chemical properties. The role of materials chemistry and microstructure. Biocompatibility. Case studies (dental and orthopedic implants, stents, nonporous ceramic filters for kidney dialysis). Prerequisites BioE 110 or MAT 33, or consent of instructor. Misiolek

BioE 335 BioFluid Mechanics of Physiological Systems (3)

Application of advanced fluid dynamic principles to physiological systems with emphasis on micron sized structures such as pulmonary airway/alveoli, small blood vessels and biological cells. Introduction to advanced topics relevant to the human body including a) oscillatory and transient flows in the cardiovascular and pulmonary systems b) nonNewtonian flows, c) surface tension driven flows, d) fluidstructure interactions, and e) cellular fluid mechanics. Prerequisites Math 205, Math 231, and ME 231 or an equivalent introductory fluid mechanics course, or instructor permission.

BioE 343 Integrated Biotechnology Laboratory (3) fall and spring

Biosafety, sterilization, media formulation, biochemical and enzyme assays, recombinant DNA technique, protein and DNA isolation and purification, for microbial fermentation and animal cell culture. Integration of biotechnology techniques for biopharmaceutical production. Prerequisite BioE 110, ChE 341, and permission of instructor.

BioE 350 Special Topics (1-4) spring

Special topics of study in bioengineering. Permission of Instructor.

BioE 357 Integrated Biostructural Mechanics Laboratory (2) fall and spring

Basic concepts of bioengineering design through experimental designs and procedures involving cells and tissues and their interface with synthetic implants. Experimental techniques include surface characterization and interactions, spectroscopy, and advanced techniques in microscopy. Nerve action, electrocardiography, mechanics of muscle, membranes and other model systems in vitro. Prerequisite BioE 110, and permission of instructor.

Biological Sciences

Professors. Murray Itzkowitz, Ph.D. (Maryland), Chair; Barry Bean, Ph.D. (Rockefeller); Michael J. Behe, Ph.D. (Pennsylvania); Lynne Cassimeris, Ph.D. (North Carolina); David Cundall, Ph.D. (Arkansas); Linda J. LoweKrentz, Ph.D. (Northwestern); John Nyby, Ph.D. (Texas); Jeffrey A. Sands, Ph.D. (Penn State); Jill Schneider, Ph.D. (Wesleyan); Neal Simon, Ph.D. (Rutgers); Jennifer Swann, Ph.D. (Northwestern).

Associate Professors. Michael R. Kuchka, Ph.D. (Carnegie Mellon); Colin Saldanha, Ph.D. (Columbia); Robert V. Skibbens, Ph.D. (North Carolina); Vassie C. Ware, Ph.D. (Yale).

Assistant Professors. Michael Burger, Ph.D. (Texas); Matthias Falk, Ph.D. (Heidelberg); Mary Kathryn Iovine, Ph.D. (Washington); Stefan Maas, Ph.D. (Heidelberg); Sean P. Mullen, Ph.D. (Cornell)

Professor of Practice. Jutta Marzillier, Ph.D. (Heidelberg). The biological sciences include the study of living systems at levels ranging from the structure and function of molecules to the behavior and evolution of communities of organisms. The department offers four different routes to mastering skills and knowledge in this broad area. The

B.A. and B.S. programs in biology provide a broad introduction to biology with opportunities for students to create a program of study suited to their specific interests. Programs of study focused on particular aspects of biology are the B.A. and B.S. degree in the areas of behavioral neuroscience and molecular biology. For programs in biochemistry and bioengineering, see those separate sections in the catalog.

The Department of Biological Sciences strongly supports the positions of both the American Association for the Advancement of Science and the National Academy of Sciences that intelligent design is not scientific and should not be presented as science in science classes.

The requirements for the B.A. and B.S. in biology, behavioral neuroscience, and molecular biology are listed below. Research interests of the faculty and instrumentation are described in the section on graduate education.

B.A. with Major in Biology

College and university requirements for all majors (25 credit hours)

Major Program (49-50 credit hours)

Biology (30 credit hours)

*Approved electives (18 credit hours, no more than 3 cr. from the following courses: 161, 261, 262, 391, 393, College scholar project, not BIOS 130).

Mathematics (78 credit hours)

MATH 51 Survey of Calculus I (4)
MATH 52 or Survey of Calculus II (3)
MATH 12 or Basic Statistics (4)
BIOS 130 Biostatistics (4)

Collateral Sciences (12 credit hours)

CHM 30 Introduction to Chemical Principles (4)
CHM 110, 111 Organic Chemistry I and lab (3,1)
CHM 112, 113 Organic Chemistry II and lab (3,1)

The B.S. in Biology

The Bachelor of Science in biology offers broad scientific preparation in biology to facilitate advanced work in the life sciences. Progression through the program is best served through early commitment.

Requirements for the B.S. in Biology

College and university requirements as above (25 credit hours)

Major Program (73-74 credit hours)

Biology (37 credit hours)

BIOS 41 Biology Core I: Cellular and Molecular (3)
BIOS 42 Biology Core I: Cellular and Molecular Lab (1)
BIOS 115 Biology Core II: Genetics (3)
BIOS 116 Biology Core II: Genetics Laboratory (1)
BIOS 120 Biology Core III: Integrative and Comparative (4)
BIOS 317 Evolution (3)
Electives* Biology electives (22)

*Biology electives must include one course from list A, one course from list B and at least four credits of laboratory experience (e.g. two 2 credit laboratory courses). These will be chosen in consultation with the major advisor.

List A

BIOS 276 Behavioral Neuroscience II (3)
BIOS 313 Vertebrate Histology (4)
BIOS 314 Vertebrate Development (3)
BIOS 335 Animal Behavior (3)
BIOS 337 Behavioral Ecology (3)
BIOS 382 Endocrinology of Behavior (3)

List B

BIOS 324 Bacteriology (3)
BIOS 345 Molecular Genetics (3)
BIOS 353 Virology (3)
BIOS 356 Human Genetics and Reproduction (3)
BIOS 367 Cell Biology (3)
BIOS 371 Elements of Biochemistry I (3)

Mathematics (11-12 credit hours minimum)

MATH 21, 22 or Calculus I, II (8)
MATH 51, 52 Survey of Calculus I, II (7)
BIOS 130 Biostatistics (4)

Collateral Sciences (25 credit hours)

CHM 30, 31 or 40, 41 Introductory Chemistry I, II (8)
CHM 110, 112 Organic Chemistry I, II (6)
CHM 111, 113 Organic Chemistry Laboratory I, II (2)
PHY 10 or General Physics I (4)
PHY 11 Introductory Physics I (4)
PHY 12 Introductory Physics Laboratory I (1)
PHY 13 General Physics II (3)
PHY 22 Physics Lab II (1)

Recommended B.S. Biology Sequence

Freshman year

BIOS 41 Biology Core I: Cellular and Molecular (3)
BIOS 42 Biology Core I: Cellular and Molecular Laboratory (1)
MATH 51, 52 Survey of Calculus I, II (7)
CHM 30, 31 Introductory Chemistry I, II (8)
Dept 90 First Year Seminar (3)

Sophomore year

BIOS 115 Biology Core II: Genetics (3)
BIOS 116 Biology Core II: Genetics Laboratory (1)
CHM 110, 111, 112, 113 Organic Chemistry and Laboratory (8)
BIOS 120 Biology Core III: Integrative and Comparative (4)
BIOS 130 Biostatistics (4)

Junior year

PHY 10, 12 General Physics I and Laboratory (5)
PHY 13, 22 General Physics II and Laboratory (4)
Approved biology electives including one from list A and one from list B (9-12)

Senior year

BIOS 317 Evolution (3)
Electives Biology electives including at least 4 credits of laboratory (10-14)

Minor in Biology

A minor in biology may be achieved by completing the following requirements (21-22 credits):

BIOS 41, 42 Biology Core I: Cellular and Molecular and Laboratory (4)
BIOS 115, 116 Biology Core II: Genetics and Laboratory (4)
BIOS 120 or Biology Core III: Integrative and Comparative (4)
BIOS 177 Behavioral Neuroscience I (3)
CHM 110 Organic Chemistry (3)
Elective Biology electives at the 200 or 300 level (3 or 4)

B.A. with major in Behavioral-Neuroscience

The B.A. in Behavioral Neuroscience is a natural science major for B.A. distribution purposes.

Required Major Courses

BIOS 41 Biology Core I: Cellular and Molecular (3)
BIOS 42 Biology Core I: Cellular and Molecular Laboratory (1)
BIOS 115 Biology Core II: Genetics (3)
BIOS 116 Biology Core II: Genetics Laboratory (1)
BIOS 120 Biology Core III: Integrative and Comparative (4)
BIOS 130 Biostatistics (4)
BIOS 177 Behavioral Neuroscience I (3)
BIOS 276 Behavioral Neuroscience II (3)
BIOS 277 Experimental Neuroscience Laboratory (2)
BIOS 382 Endocrinology of Behavior (3)

Major Electives (6 credits)

BIOS 234 Comparative Vertebrate Anatomy (4)
BIOS 307 Male Reproductive Biology (3)
BIOS 313 Vertebrate Histology (4)
BIOS 314 Vertebrate Development (3)
BIOS 317 Evolution (3)
BIOS 324 Bacteriology (3)
BIOS 328 Immunology (3)
BIOS 335 Animal Behavior (3)
BIOS 337 Behavioral Ecology (3)
BIOS 345 Molecular Genetics (3)
BIOS 353 Virology (3)
BIOS 356 Human Genetics and Reproduction (3)
BIOS 365 Neurobiology of Sensory Systems (3)
BIOS 367 Cell Biology (3)
BIOS 368 Cell Biology Laboratory (2)
BIOS 369 Comparative Physiology of Vertebrate Systems (3)
BIOS 371 Elements of Biochemistry I (3)
BIOS 372 Elements of Biochemistry II (3)
BIOS 376 Classical and Molecular Embryology (3)
BIOS 377 Biochemistry Laboratory (3)
BIOS 384 Eukaryotic Signal Transduction (3)
PSYC 117 Cognitive Psychology (3)
PSYC 153 Personality (4)
PSYC 154 Introduction to Clinical Psychology (3)
PSYC 176 Mind and Brain (4)
PSYC 305 Abnormal Psychology (4)
PSYC 307 Seminar in Cognition (4)

Required Collateral Courses

MATH 21, 22 or Calculus I, II (8)
MATH 51, 52 Survey of Calculus I, II (7)
CHM 30 Introduction to Chemical Principles (4)
CHM 110, 112 Organic Chemistry (6)
CHM 111, 113 Organic Chemistry Laboratory I, II (2)
PSYC 1 Introduction to Psychology (4)

Other Options

The B.A. in Behavioral Neuroscience can be structured for a wide variety of possibilities (see listing of recommended elective courses). By using free electives to take additional science, the B.A. also can serve as a preprofessional degree for many graduate and professional schools. Students interested in a particular careerbased program should consult their advisor or the program director, Professor John Nyby.

B.S. in Behavioral Neuroscience

B.S. majors are required to take the required major courses of the B.A. program and to fulfill the elective requirements of the B.A. program. An early commitment to the B.S. is desirable to meet all the requirements of this program. Additional requirements are shown below.

Additional Biological Sciences Requirements for the B.S.

BIOS 371, 372 Elements of Biochemistry I & II (6)
BIOS 365 or Neurobiology of Sensory Systems (3)
BIOS 234 or Comparative Vertebrate Anatomy (4)
BIOS 377 or Biochemistry Laboratory (3)
BIOS 368 Cell Biology Laboratory (2). If this course is elected, Cell Biology BIOS 367 must be taken as an elective

Math and Science Requirements for the B.S.

MATH 21, 22 or Calculus I, II (8)
MATH 51, 52 Survey of Calculus I, II (7)
CHM 30 Introduction to Chemical Principles (4)
CHM 31 Chemical Equilibria in Aqueous Systems (4)
CHM 110, 112 Organic Chemistry I, II (6)
CHM 111, 113 Organic Chemistry Laboratory (2)
PHY 10, 12 or General Physics I and Laboratory (5)
PHY 11, 12 Introductory Physics I and Laboratory (5)
PHY 13, 22 or General Physics II and Laboratory (4)
PHY 21, 22 Introductory Physics II and Laboratory (5)
PSYC 1 Introduction Psychology (4)

B.A. with Major in Molecular Biology

Requirements for the B.A. in Molecular Biology

College and university requirements (see above).

Biology (34-35 credit hours)

BIOS 41, 42 Biology Core I: Cellular and Molecular (3) and Lab (1)
BIOS 115, 116 Biology Core II: Genetics (3) and Lab (1)
BIOS 120 Biology Core III: Integrative and Comparative (4)
BIOS 324 or Bacteriology (3)
BIOS 328 or Immunology (3)
BIOS 353 Virology (3)
BIOS 325 or Bacteriology Lab (2)
BIOS 368 or Cell Biology Lab (2)
BIOS 377 Biochemistry Lab (3)
BIOS 371 Elements of Biochemistry I (3)
BIOS 345, 346 Molecular Genetics (3) and Lab (2)
BIOS 367 Cell Biology (3)
BIOS approved electives (6 credit hours)

Mathematics (7-8 credit hours)

MATH 21, 22 or Calculus I, II (8)
MATH 51, 52 Survey of Calculus I, II (7)

Chemistry (16 credit hours)

CHM 30 Introduction to Chemical Principles (4)
CHM 31 Chemical Equilibria in Aqueous Systems (4)
CHM 110, 111, 112, 113 Organic Chemistry I, II and Lab I, II (8)

Physics (9 credit hours)

PHY 10, 12 or General Physics I and Lab I (5)
PHY 11, 12 Introductory Physics I and Lab (5)
PHY 13, 22 General Physics II and Lab (4)

The B.S. in Molecular Biology

Requirements for the B.S. in Molecular Biology

Major Program (82-85 credit hours)

Mathematics (11-12 credit hours)

MATH 21, 22 or Calculus I, II (8)
MATH 51, 52 Survey of Calculus I, II (7)
BIOS 130 Biostatistics (4)

Chemistry (16 credit hours)

CHM 30 Introduction to Chemical Principles (4)
CHM 31 Chemical Equilibria in Aqueous Systems (4)
CHM 110, 112 Organic Chemistry I, II (6)
CHM 111, 113 Organic Chemistry Laboratory (2)

Physics (9-10 credit hours)

PHY 10 (or 11) General Physics I (4)
PHY 12 Introductory Physics Laboratory I (1)
PHY 13 (or 21) General Physics II (3 or 4)
PHY 22 Physics Lab II (1)

Molecular Biology (46-47 credit hours)

BIOS 41 Biology Core I: Cellular and Molecular (3)
BIOS 42 Biology Core I: Cellular and Molecular Lab (1)
BIOS 115 Biology Core II: Genetics (3)
BIOS 116 Biology Core II: Genetics Laboratory (1)
BIOS 120 Biology Core III: Integrative and Comparative (4)
BIOS 324 or Bacteriology (3)
BIOS 328 or Immunology (3)
BIOS 353 Virology (3)
BIOS 325 or Bacteriology Laboratory (2)
BIOS 368 or Cell Biology Laboratory (2)
BIOS 377 Biochemistry Laboratory (3)
BIOS 345 Molecular Genetics (3)
BIOS 346 Molecular Genetics Laboratory (2)
BIOS 367 Cell Biology (3)
BIOS 371 Elements of Biochemistry I (3)
BIOS 372 Elements of Biochemistry II (3)
BIOS 381 Physical Biochemistry (3)
BIOS Approved Molecular Biology Electives (12)

Recommended sequence for the B.S. in Molecular Biology Freshman year

BIOS 41 Biology Core I: Cellular and Molecular (3)
BIOS 42 Biology Core I: Cellular and Molecular Laboratory (1)
MATH 21, 22 Calculus I, II (8)
CHM 30 Introduction to Chemical Principles (4)
CHM 31 Chemical Equilibria in Aqueous Systems (4)

Sophomore year

BIOS 115 Biology Core II: Genetics (3)
BIOS 116 Biology Core II: Genetics Laboratory (1)
BIOS 120 Biology Core III: Integrative and Comparative (4)
CHM 110, 112 Organic Chemistry I,II (6)
CHM 111, 113 Organic Chemistry Laboratory (2)
PHY 10, 12 General Physics I and Lab (5)
PHY 13, 22 General Physics II and Laboratory (4)

Junior year and Senior year

BIOS 324 or Bacteriology (3)
BIOS 328 or Immunology (3)
BIOS 353 Virology (3)
BIOS 325 or Bacteriology Laboratory (2)
BIOS 368 or Cell Biology Laboratory (2)
BIOS 377 Biochemistry Laboratory (3)
BIOS 345 Molecular Genetics (3)
BIOS 346 Molecular Genetics Laboratory (2)
BIOS 371, 372 Elements of Biochemistry I, II (6)
BIOS 367 Cell Biology (3)
BIOS 381 Physical Biochemistry (3)
BIOS Approved Molecular Biology Electives (12)

Molecular Biology Minor

The molecular biology minor program consists of BIOS 41 (3), 42 (1), 115 (3), 116 (1), 345 (3), 346 (2), and a minimum of 4 additional credits of BIOS coursework at the 200 or 300 level. Collateral coursework must include: MATH 51 or 21 (4), CHM 30 (4), and CHM 110 (3).

Departmental Honors

A student may apply for admission to the departmental honors program through a potential thesis advisor. Requirements for Departmental Honors include a major GPA of 3.25 and at least 2 semesters of research for a minimum of 6 cr. The student must write a research proposal for their project and a thesis at the conclusion of their research. This work must be presented in a symposium at the end of the project. Students must meet regularly to discuss their research progress in BIOS 387 and BIOS 388 to facilitate progress in the research project.

Undergraduate Courses in Biological Sciences

Courses with numbers below 010 are intended for nonmajors and may not be used to satisfy any life science major or minor requirement.

BIOS 1. Biology for Non-Majors (3 or 4)

Basic and applied biology for nonscience majors. May not be used in satisfaction of life science major or minor programs. Focus of topics at the discretion of the instructor. May be taught with (4 credits) or without (3 credits) a laboratory. (NS)

BIOS 7. Human Reproduction (3)

Basic and applied human reproductive biology for nonscience majors. May not be used in life science major or minor programs. (NS)

BIOS 8. Drugs and Behavior (3)

Basic principles of drug action in the central nervous system. Effects of stimulants, depressants, intoxicants and drug abuse on behavioral function. Clinical use of drugs in the treatment of various psychological and psychiatric disorders. (NS)

BIOS 10. Bioscience in the 21^st Century (4)

A multidisciplinary survey of advances in bioscience. Exploration of themebased topics (e.g., infectious diseases, cancer, genomebase medicine, engineered biomedical systems) coupled with social/ethical considerations. Three lectures per week. Participation in online multidisciplinary discussion, writing assignments, field trips, and/or other activities. (NS)

BIOS 41. Biology Core I: Cellular and Molecular (3)

Basic building blocks and higherorder structures required for cellular processes. Topics include the character of membranes, the molecular/cellular basis of energy production, cell cycle progression, DNA replication, gene expression, signal transduction, and cell division. Preor corequisite: CHM 30 or 40. (NS)

BIOS 42. Biology Core I: Cellular and Molecular Lab (3)

Experiments, observations, and discussions related to the principal topics covered in BIOS 41. Corequisite: BIOS 41.

BIOS 115. Biology Core II: Genetics (3)

The structure, function, and continuity of hereditary information. Classical genetic analysis. Molecular biology of genes and genomes. Population genetics and evolution. Genetics of complex traits. Prerequisite: BIOS 41. (NS)

BIOS 116. Biology Core II: Genetics Laboratory (1)

Laboratory work that demonstrates major principles of genetics: included are experiments on microorganisms and the common fruit fly, Drosophila melanogaster. Prerequisite: BIOS 115, preferably concurrently.

BIOS 120. Biology Core III: Integrative and Comparative (4)

Experimental and historical approaches to the analysis of structural and functional properties in organisms. Use of scientific method to study species diversity. Introduction to the analysis of organismal attributes that explain behavioral repertoire and ecological relationships. Prerequisites: BIOS 115, 116 (NS).

BIOS 130. Biostatistics (4)

Elements of statistics and probability theory with emphasis on biological applications. Statistical analysis of experimental and observational data. Prerequisite: BIOS 41 and MATH 52 or MATH 22 (ND)

BIOS 161. Supervised Research (13) fallspring

Apprenticeship in ongoing faculty research program. Literature review, experimental design, data collection and analysis, and professional writing under faculty sponsor supervision. May be repeated but only 3 credits can be counted toward any life science major. Prerequisite: BIOS 41 and consent of instructor. (ND)

BIOS 177. Behavioral Neuroscience I (3)

Nervous system functioning with varying emphasis on neurophysiology, neuroanatomy, behavior genetics, information transmission, research techniques, sensory and motor functions. Prerequisite: BIOS 41. (NS)

BIOS 202. Biomedical Externship (13)

Analysis of individualized experiences at external biomedical clinical or research sites. Limited enrollment. May not be taken for passfail grading. May be taken only once and may not be used to satisfy any life science major or minor requirement. Prerequisite: Consent of department chair required. (NS)

BIOS 233. Invertebrate Zoology (4)

Survey of representative invertebrates. Structure and behavior of selected types and concepts of evolutionary relationships among the major groups. Two lectures and two laboratory periods. Prerequisite: BIOS 120. (NS)

BIOS 234. Comparative Vertebrate Anatomy (4)

A course in vertebrate zoology with emphasis on the study of homologous body structures in the various vertebrate classes and their relationship to the functional demands of habit and environment in each class. Detailed dissections of representative vertebrates are made in the laboratory. Two lectures and two laboratory periods. Prerequisite: BIOS 120. (NS)

BIOS 235. Human Physiology (4)

Movement, digestion, respiration, circulation and excretion. Sensory systems, hormonal and electrical signal transduction, reproduction. Writing intensive. Prerequisite: BIOS 120 (NS)

BIOS 241. Vertebrate Natural History (4)

An introduction to the ecology, behavior, distribution and evolution of vertebrates, with emphasis on the North American fauna. Two lectures, one tutorial and one laboratory and field trip. This course may be used to fulfill junior writing requirements with the permission of the instructor. Prerequisite: BIOS 120. (NS)

BIOS 251. Writing and Biological Sciences (3)

A course designed to acquaint students with some of the intellectual foundations of science, with attention to the distinctiveness of the biological sciences. Format includes readings, intensive writing, extemporaneous speaking, and discussion. May not be used to fulfill Biology B.A. elective requirements. Prerequisite: Major status and consent of department. (NS)

BIOS 261. Special Topics in Biological Sciences (13)

Research, conferences and reports on selected topics not covered in the general undergraduate offerings. May be taken more than once for credit. Prerequisite: Major status and consent of instructor. (NS)

BIOS 262. Research Proposal (3)

Literature and methods of research in area of department faculty expertise. Requires development of detailed proposal for research to be performed in senior year. Prerequisites: Major in any biological sciences degree program; junior standing; GPA of 3.0 in major; and consent of department. (NS)

BIOS 276. Behavioral Neuroscience II (3)

Neuronanatomy and neurophysiology of animal and human behavior. Feeding, thirst, sleep, emotions, learning, and psychopathology. Prerequisite: BIOS 177. (ND)

BIOS 277. Experimental Neuroscience Laboratory (2)

Structure and function of the mammalian brain with special attention to cellular morphology and organization. Standard, cutting edge techniques to determine how the shape and function of the nervous system regulates behavior. Experimental design, hypothesis testing, statistical analysis, reading and writing of scientific papers, basic histology and imaging. Prerequisites: BIOS 177. (NS)

For Advanced Undergraduates and Graduate Students

BIOS 307. Male Reproductive Biology (13)

Molecular, cellular, and genetic aspects of the mammalian male reproductive system. Prerequisites: BIOS 120 and consent of instructor (NS).

BIOS 313. Vertebrate Histology (3)

Microstructural and ultrastructural properties of vertebrate cells and tissues. Techniques of tissue preparation. One lecture and two labs. Prerequisite: BIOS 120 (ND)

BIOS 314. Vertebrate Development (3)

Germ cell formation, fertilization, early development, and the origin of the principal organ systems. Location, structure, and regulation of information from molecular to organismal levels of organization. Prerequisite: BIOS 120 (NS)

BIOS 317. Evolution (3)

Mechanisms of evolution, emphasizing genetic structure and variation of populations, and isolation. Origin of species and higher taxa. Rates of evolution, extinction. Prerequisite: BIOS 120 (NS)

BIOS 320. The Business of Life Science (3)

An examination of business process in startup, early stage and developing bioscience companies. Technology assessment, business plan and proposal preparation, financial strategies, resource management, intellectual property, and legal as well as regulatory issues. Cannot be used to fulfill major requirements in Biological Sciences. Prerequisite: BIOS 120 or consent of instructor. (ND)

BIOS 324. Bacteriology (3)

The structure, physiology, growth, genetics and taxonomy of prokaryotes. Prerequisites: CHM 110 and BIOS 120. (NS)

BIOS 325. Bacteriology Laboratory (2)

Standard procedures and metabolic tests used in determinative bacteriology; aseptic technique, sterilization, enumeration, and control of bacterial growth; other selected topics. Corequisite: BIOS 324.

BIOS 328. Immunology (3)

Distinction of "self" and "nonself" through humoral and cellular mechanisms. Antigens; biochemical structures, cellular mechanisms, genetic control and processing, phylogenetic distribution, diseased states. Prerequisite: BIOS 120. (NS)

BIOS 329. Herpetology (3)

Biology of amphibians and reptiles. Two lectures, one laboratory or field trip per week. Prerequisite: BIOS 120. (ND)

BIOS 334. Species and Speciation (3)

Consideration of the origin of species. Discussion of a variety of "species" definitions and exploration of the evolutionary mechanisms by which new species arise. Alternation between lecture and discussion, drawing on the textbook and on current and classical literature. Prerequisite: BIOS 317.

BIOS 335. (PSYC 335) Animal Behavior (3)

Discussion of the behavior of invertebrates and vertebrates and analysis of the physiological mechanisms responsible for behavioral stimuli, and adaptive value of specific behavior patterns. Prerequisite: BIOS 120. (NS)

BIOS 336. Animal Behavior Laboratory (2)

Experiments and field observations illustrating principles discussed in BIOS 335. Emphasis on observing animals, performing experiments, collecting and analyzing data, and individual research. Six hours of laboratory per week. Corequisite: BIOS 335 or 337.

BIOS 337. Behavioral Ecology (3)

Social systems of vertebrate and invertebrate groups. Emphasis on ecological and evolutionary factors that influence social behavior. Prerequisite: BIOS 120. (NS)

BIOS 340. Molecular Basis of Disease (3)

Lectures and student projects on molecular mechanisms of human disease. Physiology of disease, molecular mechanisms, therapeutic approaches, ongoing research. Topics include: neurodegenerative diseases, cancer, autoimmune diseases, infectious diseases. Prerequisite: BIOS 120 (NS)

BIOS 345. Molecular Genetics (3)

The organization and replication of genetic material; mutagenesis; mechanisms of regulation; mechanisms of gene transmission involving prokaryotes and eukaryotes and their viruses; techniques for intervention into genetic organization and expression. Prerequisite: BIOS 120. (NS)

BIOS 346. Molecular Genetics Laboratory (2)

Laboratory experiments related to the topics covered in BIOS 345. Emphasis is on molecular characterization of DNA and the principles of gene isolation and transfer. Corequisite: BIOS 345.

BIOS 347. Advanced Topics in Genetics (3)

Lectures and student projects on selected aspects of genetics such as the genetics and evolution of particular organisms, regulation of gene expression and transmission, human genetics, gene therapy, etc. Prerequisites: BIOS 345 or consent of department chair. (NS)

BIOS 353. Virology (3)

Structure and replication of viruses. Emphasis on the organization, replication, and regulation of expression of viral genomes; the mechanisms of virus assembly and release; and on virushost interactions. Special attention given to human pathogenic viruses. Prerequisite: BIOS 120 and CHM 112. (NS)

BIOS 356. Human Genetics and Reproduction (3)

Frontiers in human genetics, including simple and complex genetic diseases, cancers. Emphasis on genes and structures that enable reproductive processes; genetic functions of mammalian germ lines. Analysis of current publications. Prerequisite: BIOS 120. (NS)

BIOS 365. Neurobiology of Sensory Systems (3)

The fundamental features of sensory systems in a diverse array of animals. Focus on how nervous systems detect, compute, and internally represent aspects of the environment from the single cell to whole system level. Special attention to the way sensory processing influences how we think about the biological basis of perception and possible mechanisms for consciousness. Prerequisites: BIOS 177 and 120.

BIOS 367. Cell Biology (3)

Molecular aspects of cell biology. Emphasis on membrane structure and function, organelle biogenesis, cell motility, the cytoskeleton, and extracellular matrix. Prerequisite: BIOS 120. (NS)

BIOS 368. Cell Biology Laboratory (2)

Basic methods used in cell biology laboratories around the world and the opportunity to carry out an independent research project. Techniques include histology and microscopy (both white and fluorescent light), tissue culture and sterile procedures, cellular fractionation, nuclear import assays, and immunological probing. Coor prerequisite: BIOS 367. Consent of Department. (NS)

BIOS 369. Comparative Physiology of Vertebrate Systems (34)

Functional analysis of energy balance in vertebrate animal models. Digestion, respiration, circulation, and excretion, across aquatic and terrestrial vertebrates. Homeostatic mechanisms of salt, water, and gas exchange. Ionotropic and metabetropic signal transduction. Hormonal and electrical cellular communication among muscles, glands, and neurons. Sensory systems, movement and reproduction. Physiological adaptations to extreme environments. When offered for 4 credits, the course includes one laboratory meeting per week. Prerequisite: BIOS 120. (NS)

BIOS 371. (CHM 371) Elements of Biochemistry I (3) fall

A general study of carbohydrates, proteins, lipids, nucleic acids and other biological substances and their importance in life processes. Protein and enzyme chemistry are emphasized. Prerequisite: one year of organic chemistry. (NS)

BIOS 372. (CHM 372) Elements of Biochemistry II (3) spring

Dynamic aspects of biochemistry; enzyme reactions including energetics, kinetics and mechanisms; metabolism of carbohydrates, lipids, proteins and nucleic acids; photosynthesis, electron transport mechanisms, coupled reactions, phosphorylations, and the synthesis of biological macromolecules. Prerequisite: BIOS 371 and BIOS 41 or consent of the instructor. (NS)

BIOS 376. Classical & Molecular Embryology (3)

Differentiation of multicellular organisms from a single cell. Axis determination; gradients; induction and pattern formation viewed through modern analysis of regulated gene expression. Prerequisite: BIOS 345 (previously or concurrently). (NS)

BIOS 377. (CHM 377) Biochemistry Laboratory (3) fall

Laboratory studies of the properties of chemicals of biological origin and the influence of chemical and physical factors on these properties. Laboratory techniques used for the isolation and identification of biochemicals. Prerequisite: BIOS/CHM 371 previously or concurrently and BIOS 41 or consent of instructor. (ND)

BIOS 378. (CHM 378) Biochemical Preparations (13) spring

A laboratory course involving the preparation or isolation, purification and identification of chemicals of biological origin. Prerequisites: BIOS/CHM 377 and 372, previously or concurrently. (ND)

BIOS 381. Physical Biochemistry (3)

Topics include: thermodynamics of biological systems; Forces acting on and between biological molecules; Principles of macromolecular structure; Physical methods used to characterize biomolecules; and other topics to be determined. Prerequisite BIOS/CHM 371 and BIOS 41. (NS)

BIOS 382. (PSYC 382) Endocrinology of Behavior (3)

Hormonal effects upon animal and human behavior. Emphasis on neuroendocrinology of steroid hormone involvement in reproductive behaviors. Prerequisite: BIOS 177 or BIOS 120. (NS)

BIOS 383. Biological Sciences Colloquia (1)

Analysis of weekly colloquia in the biological sciences. For senior majors in the biological sciences. May be taken twice for credit. (ND)

BIOS 384. Eukaryotic Signal Transduction (3)

Signal transduction between cells of multicellular eukaryotic organisms examined in the context of specialized functions that include: nutrition, hormones and neurotransmitters, vision, muscle contraction, adhesion, and the immune system. The evolution of cancer based on mutations in these signaling systems. Prerequisite BIOS 367 or 372.

BIOS 387. Biological Sciences Honors Seminar (1)

Development, presentation and implementation of research proposals, and discussions of research. Required for senior biology and molecular biology majors pursuing departmental honors. Departmental permission required. (ND)

BIOS 388. Biological Sciences Honors Seminar (1)

Continuation and extension of BIOS 387. Departmental permission required. (ND)

BIOS 391. Undergraduate Research (13)

Laboratory research under tutorial with a faculty member. May be taken more than once for credit. Prerequisites: junior standing, and consent of instructor. (ND)

BIOS 393. Thesis (3)

Literature review and design of project in selected area, execution of the project, final report and presentation. Departmental permission. Intended for senior majors in BIOS only. May be repeated one time for additional credit. Prerequisite: Consent of instructor. (ND)

Special Health Professions Programs

Students may apply for admission to an accelerated B.A.Doctor of Medicine program and a B.A.Doctor of Medical Dentistry program. A sevenyear B.A.M.D. program is offered in conjunction with Drexel University College of Medicine, and a sevenyear B.A.D.M.D. program is offered in conjunction with the University of Pennsylvania School of Dental Medicine. Students in these programs receive a B.A. from Lehigh and a graduate degree from the designated professional school within a sevenyear period. For details concerning admission to these programs, see Health Professions, Section III.

Graduate Study in the Biological Sciences

Rigorous, researchoriented graduate programs leading to a Doctor of Philosophy are offered in three divisions of the Department of Biological Sciences: biochemistry, integrative biology and neuroscience, and molecular biology. To complete the program students must successfully complete core courses, pass a qualifying exam, prepare, submit, and successfully defend a written research proposal, complete the research described in the proposal, and submit a written dissertation and defend the completed research to the department.

Once students enter the department, their progress is monitored by the graduate committee until they are admitted to candidacy. Members of the committee meet with the student each semester to assess the student's progress towards the degree and to assist students in choosing the appropriate courses to provide a solid scientific foundation and an uptodate understanding of the discipline. This will be assessed by the qualifying exam.

The qualifying exam generally should be taken after the third semester and no later than the fourth semester of course work. It will be prepared, administered and graded by the faculty associated with the specific graduate program in which the student is enrolled. It consists of a twoday written exam and an oral examination. The exam can be repeated once. Admission to candidacy is granted after successful completion of the qualifying exam and the thesis proposal. The proposal is a written description of an original research project developed under the guidance of a faculty member chosen by the student to be his/her advisor. The proposal will be presented orally to the thesis committee, typically after the fifth semester. Following the presentation of the proposal, an oral examination will take place in which the thesis committee will question the student about general science related to the project. This will constitute the general examination.

Core requirements for each division are listed below. The graduate school requires students to register for at least 72-post baccalaureate credits to earn the Ph.D. In addition, all students must take BIOS 408 (0 credits) Responsible Conduct of Science within their first year of graduate study. All students must also attend departmental seminars and enroll in BIOS 406 (1 credit) Biological Sciences Seminar at least twice in the first four semesters. A minimum of 24 course credits may be chosen from upper level courses in biochemistry, molecular biology, cell biology, behavioral biology and evolutionary biology, and neuroscience. At least 12 of these credits must be at the 400 level.

In the biochemistry program, research areas include DNA structure and function, regulation of protein synthesis, and signal transduction. Students admitted to graduate study in biochemistry will typically have an undergraduate degree in chemistry or biochemistry. Students with an undergraduate degree in a related discipline will be expected to have the following undergraduate preparation for graduate study beyond introductory chemistry and a year of organic chemistry: at least one semester of analytical chemistry and one semester of physical chemistry thermodynamics and kinetics, with appropriate math. Students without that background will be expected to take courses to fulfill those requirements as part of their graduate study. Required courses: BIOS 371, 372 Elements of Biochemistry I and II, BIOS 469, 470 Biochemical Problem Solving I and II, CHM 423 BioOrganic Chemistry, BIOS 345 Molecular Genetics, and a seminar course. BIOS 408 or CHM 400 must also be completed before beginning research.

The graduate program in integrative biology and neuroscience is designed to train students in advanced organismal biology with the emphasis on behavioral ecology, evolution, functional morphology, endocrinology, and neurobiology of animals. The mission of the program is to create students who are broadly trained and uniquely capable of asking questions and solving problems at the interface of these traditionally defined fields. Students admitted to the program should have a basic knowledge of evolution, anatomy, physiology, behavioral neuroscience, and/or behavioral ecology. Students will begin by taking core courses providing a broad foundation in integrative biology at the graduate level and work toward a Ph.D. with a concentration in either behavioral neuroscience or behavioral and evolutionary biology. Regardless of concentration, all students in the program develop an appreciation for the fact that all aspects of biology, whether cellular, physiological, anatomical, behavioral, evolutionary, or social, are inextricably linked and cannot be fully understood as separate, parallel systems of knowledge. The integrative program consists of two tracts: (I) Animal Behavior and Evolution, and (II) Neuroscience. The Animal Behavior and Evolution tract requires that students take 4 core courses with at least one course taken from each of the following three core areas: (1) Animal Behavior/Evolution (courses include BIOS 409, 439, 334). (2) Behavior/Neuroanatomy (BIOS 453, 475) and (3) Development/Neurophysiology (BIOS 416, 450). The Neuroscience tract requires that students take both BIOS 453 and 416, and one course from each of the following core areas: (1) Developmental/Endocrinology (BIOS 450, 457), (2) Animal Behavior/Evolution (BIOS 409, 439, 334), (3) Cell/Molecular Neuroscience (411, 421, 422, 431, 432). BIOS 401 and two semesters of BIOS 406 are required. Depending on the student's background, additional courses may be required.

In the molecular biology program, research areas include microbial evolution and genetics, plant and animal molecular genetics, eukaryotic cell biology, and regulation of gene expression. Required core courses include BIOS 345 Molecular Genetics, BIOS 371 Elements of Biochemistry I, BIOS 372 Elements of Biochemistry II, BIOS 411 Advanced Cell Biology, BIOS 421 Molecular Cell Biology I, and BIOS 422 Molecular Cell Biology II. Additional courses to reach 24 credits are chosen from upper level electives in molecular biology, cell biology, and biochemistry.

Facilities available for research in the biological sciences include core facilities with equipment (for example, for DNA synthesis, confocal microscopy, digital imaging, chromatography, cell culture, centrifugation, controlled environments, gamma and scintillation counting, flow cytometry, and rodent surgery). Individual research laboratories and advanced teaching laboratories contain a variety of additional equipment. Ongoing interactions with a variety of private companies contribute additional opportunities for student experiences.

Graduate Courses in the Biological Sciences

BIOS 401. Professional Skills for Biological Sciences Graduate Students (3)

Students learn expectations and fundamental skills related to success in the biological sciences. The course is designed to help students make the most out of their graduate education. Students learn the principles underlying fundable, publishable research, and how these general principles can be applied to their specific research area. They learn to write and review manuscripts and grant proposals by serving on a mock editorial board and scientific review panel. They gain experience in giving oral presentations. Readings are from texts on scientific writing and research styles, and from original journal articles and grant proposals written by the faculty. No prerequisites. Required of all Integrative Biology graduate students.

BIOS 404. (PSYC 404) Behavioral Neuroscience (3)

Theoretical and empirical issues in biopsychology. Prerequisite: Graduate standing or consent of instructor.

BIOS 405. Special Topics in Molecular Biology (13)

Research, conferences, and reports on selected topics not covered in the general graduate offerings. May be taken more than once for credit.

BIOS 406. Biological Sciences Seminar (1)

An advanced seminar in current developments including departmental research. Required for candidates for graduate degrees in molecular biology. May be taken more than once for credit.

BIOS 407. Research in Biological Science (19)

Laboratory investigations in one of the department's research areas.

BIOS 408. Responsible Conduct of Science (0)

Responsible practice in research. Training in general laboratory methods; human subjects concerns; radiation safety; chemical hazards; aseptic technique; physical, mechanical, biological, and fire hazards; animal welfare. Occupational and workplace considerations. Recombinant DNA guidelines; patent and proprietary rights; controversies over applications of science. Appropriate aspects required of investigators in all departmental research projects.

BIOS 409. Evolutionary and Functional Morphology (3)

Readings in the current literature, demonstrations and laboratory exercises exploring the applications of comparative methods to the analysis of evolutionary patterns at a range of morphological levels (molecular and macroscopic). Students will also learn experimental approaches to testing relationships between form and function in vertebrates. Emphasis will be on the musculoskeletal and nervous systems. Prerequisite BIOS 234, BIOS 317, or permission of instructor.

BIOS 410. Special Topics in Behavioral and Evolutionary Bioscience (13)

Readings and discussions on selected topics not covered in the general graduate offerings. May be taken more than once for credit.

BIOS 411. Advanced Cell Biology (3)

Cell structure and biochemistry, as related to specialized cell functions.

BIOS 412. Metabolic Influences on Behavior (3)

Sensory systems that detect metabolic energy availability and affect the behavior of humans and other animals: food intake and body weight regulation, sexual and parental behavior, aggression, learning, and body temperature regulation. Prerequisite: BIOS 404 and consent of instructor.

BIOS 414. Sexual Differentiation (3)

Genetic and hormonal events mediating the development and expression of sexual dimorphisms in physiology and behavior. Current theoretical models; emphasis on biochemical, neuroanatomical and molecular biological considerations. Prerequisite: BIOS 404 and consent of instructor.

BIOS 415. Neuropharmacology (3)

Mechanism of drug action in the central nervous system, including cell surface receptors and second messenger systems. Drug use/abuse and cellular changes mediating behavioral effects. Drug use in clinical therapy. Prerequisite: BIOS 404 and consent of instructor.

BIOS 418. Analysis of Reproduction and Mating Systems (3)

Study of reproduction and sexuality in plants and animals with emphasis on current hypotheses as reported in the literature. Topics include hermaphroditism, neoteny, larval forms, parental investment, complex life cycles, population structure. Readings from primary source material and review articles. One review paper and one research proposal are required, and together with readings forms the basis for discussion sections and examinations. Prerequisite: Consent of the department.

BIOS 420. Pheromonal Communication (3)

Mechanisms of pheromone synthesis, biochemistry, sensory transduction, neuroanatomy/neuroendocrinology, and adaptive significance. Prerequisite: BIOS 404 and consent of instructor.

BIOS 421. Molecular Cell Biology I (3)

Molecular aspects of cell structure, cell motility, intracellular transport; and biomembrane dynamics. Prerequisite: BIOS 411 or equivalent.

BIOS 422. Molecular Cell Biology II (3)

Molecular aspects of gene expression, including genome structure and replication, RNA synthesis/processing, and protein synthesis. Prerequisite: BIOS 345 or equivalent.

BIOS 424. Advanced Neurobiology of Sensory Systems (3)

This course is designed to provide an overview of core principles of neuroscience through exploration of sensory systems. The course will provide an intensive review of fundamental neural signaling followed by a broad introduction to the major sensory pathways. Focus will be on major organizing principles of neural systems, and information processing. Student discussions and presentations will incorporate current literature and concepts.

BIOS 425. Male Reproductive Biology (13)

Molecular, cellular, and genetic aspects of the mammalian male reproductive system. Prerequisite: Permission of instructor.

BIOS 427. Techniques in Cell and Molecular Biology (3)

Laboratory experiences in three or more cell and molecular biological techniques: gel electrophoresis of nucleic acids/proteins; polymerase chain reaction; DNA/RNA sequencing; molecular hybridization techniques; fluorescence microscopy; confocal microscopy; flow cytometry; electron microscopy tissue preparation; immunological detection methods; molecular cloning techniques; oocyte microinjection techniques; tissue culture methods; and autoradiography.

BIOS 429. Advances in Herpetology (3)

Lectures and readings from the primary literature on current research in amphibian and reptilian biology. Two lectures, one discussion session and one laboratory or field trip. Not open to students who have received credit for BIOS 329.

BIOS 431. Advanced Topics in Cell Biology (3)

Current research problems in cell biology. May be repeated when a different topic is offered. Prerequisite: BIOS 367 or equivalent.

BIOS 432. Advanced Topics in Molecular Genetics (3)

Current research in molecular genetics. May be repeated when a different topic is offered. Prerequisite: BIOS 345 or equivalent.

BIOS 433. Advanced Topics in Developmental Biology (3)

Current research problems in developmental biology. May be repeated when a different topic is offered. Prerequisite: BIOS 345 or equivalent.

BIOS 437. (CHM 437) Pathophysiological Chemistry (3)

Biochemical basis of human diseases involving abnormal metabolism of proteins, nucleic acids, carbohydrates, and lipids. Emphasis on the correlation of the clinical presentation of disease processes seen as physiological dysfunctions with clinical laboratory methods. Lectures, student presentations, and clinical case discussions. Prerequisite: consent of the department.

BIOS 439. Advanced Behavioral Ecology (3)

Critical evaluation of the theoretical foundation in sociobiology. Emphasis placed on kinship, altruism, mate choice, parental investment, parentoffspring conflict, etc. Lectures and seminars. Prerequisite: BIOS 317 or equivalent. Not open to students who have taken BIOS 337.

BIOS 445. Systematics and Evolution (3)

Theoretical, philosophical and methodological foundations of the classification of eukaryotic organisms and the manner in which systematic theory and method relate to evolutionary theory. Two lectures and one labrecitationdiscussion session. Prerequisite: BIOS 317.

BIOS 450. Developmental Neurobiology (3)

Fundamental mechanisms underlying neural development. Early events leading to the induction of the neuroectoderm and the reorganization of the vertebrate central nervous system during adulthood and aging. Major developmental events such as phenotype commitment, cell migration, differentiation and growth cone guidance. Emphasis on the interplay between concepts emerging from organismal and molecular levels of analyses.

BIOS 453. General Neuroanatomy (3)

Graduate level study of the neuroanatomy and neurochemistry of systems that underlie behavior in vertebrates. Emphasis will be on the traditional and novel methodologies used to reveal neuroanatomical pathways as well as the function of these pathways. Prerequisites: Permission of instructor.

BIOS 456. Human Genetics and Preproduction (3)

Frontiers in human genetics, including simple and complex genetic diseases, cancers. Emphasis on genes and structures that enable reproductive processes; genetic functions of mammalian germ lines. Analysis of current publications.

BIOS 457. Advanced Behavioral Neuroendocrinology (3)

A seminar course that covers current primary literature on the hormonenervous system interactions that underlie physiology and behavior. The course covers the neuroendocrinology of reproduction, sex behavior, parental behavior, social behavior, agonistic and territorial behavior, learning and memory, homeostasis (caloric, nutritional, water and salt balance, temperature regulation), circadian rhythms and seasonality in a variety of vertebrates. Prerequisite: BIOS 382 or permission of instructor.

BIOS 464. Molecular Biology of Eukaryotic Organisms (3)

Comparative analysis of several eukaryotes as model systems in cell biology, developmental biology, genetics, and molecular biology. Prerequisite: BIOS 345 or equivalent.

BIOS 466. Structure and Function of RNAs and Ribonucleoprotein Complexes (3)

Biochemistry and function of small nuclear RNPs, RNase P, ribosomes, selfsplicing introns, signal recognition particle, RNA viruses. Functions of RNA in DNA replication, in regulation, as an enzyme, and as a repressor. Prerequisite: BIOS 345 or equivalent.

BIOS 467. (CHM 467) Principles of Nucleic Acid Structure (3)

An examination of the principles underlying nucleic acid structure including stereochemistry, electrostatics, hydration, torsional constraints, sequence specific effects, and interaction with nuclear proteins. Special emphasis will be placed on DNA structure. Prerequisites: one year of biochemistry and one year of physical chemistry or permission of the department.

BIOS 468. (CHM 468) Principles of Protein Structure (3)

An examination of the principles underlying protein structure including stereochemistry, preferred tertiary structures, protein homology, excluded volume effects, time dependent structural fluctuations, and prediction of protein structure from sequence information. Prerequisites: one year of biochemistry and one year of physical chemistry or permission of the department.

BIOS 469. (CHM 469) Biochemical Problem Solving I (1)

Applications of material covered in BIOS/CHM 371 including techniques used in research. Prerequisite: BIOS/CHM 371 previously or concurrently.

BIOS 470. (CHM 470) Biochemical Problem Solving II (1)

Applications of concepts covered in BIOS/CHM 372 including techniques used in research. Prerequisite: BIOS/CHM 372 previously or concurrently.

BIOS 471. (CHM 471) Eukaryotic Signal Transduction (3)

Signal transduction between and within cells of multicellular organisms examined in the context of specialized functions that include: nutrition, hormones and neurotransmitters, vision, muscle contraction, adhesion and the immune system. The evolution of cancer based on mutations in these signaling systems. Lecture, discussion, and student presentations. Prerequisite: BIOS/CHM 372 or BIOS 411.

BIOS 472. (CHM 472) Lipids and Membranes (3)

Structure, physical properties and functions of lipids and their biological aggregates. Techniques for studying lipid assemblies, enzymes which act on lipids, membrane proteins and lipoproteins will also be discussed. Prerequisite: BIOS/CHM 372 or consent of department.

BIOS 473. (CHM 473) Biochemistry of Complex Carbohydrates (3)

Consideration of the structure, function and metabolism of complex carbohydrates (glycolipids, glycoproteins and proteoglycans) with particular emphasis on glycoproteins. The first part of the course will consist of lectures to familiarize the student with basic terms, concepts and processes. The second part will involve critical readings, presentation and discussion of the current primary research literature by class participants.

BIOS 479. (CHM 479) Biochemical Techniques (3)

Laboratory studies of the techniques and principles involved in the isolation, identification, and biochemical transformation of carbohydrates, lipids, nucleic acids and proteins. Prerequisite: BIOS 371 or its equivalent previously or concurrently.

BIOS 480. (CHM 480) Advanced Biochemical Preparations (13)

An advanced laboratory course in the preparation, isolation, purification, and identification of biochemically produced materials. Emphasis is placed on materials and procedures of current interest in biochemistry. Prerequisite: consent of the department.

BIOS 483. Special Topics in Behavioral Neuroscience (3)

Examination of the biological substrates of behavior. Topics may include animal communication, sociobiology, behavioral endocrinology, or behavior genetics. May be repeated for credit. Prerequisite: BIOS 404 or consent of department.

BIOS 488. Seminar in Neuroscience, Behavior, and Evolution (1)

Advanced seminar in current research developments. May be taken more than once for credit.

Biology

Biology, life science, and related courses at Lehigh University are offered in a variety of settings that reflect the various levels of organization in life science and different orientations relating to areas of application. The College of Arts and Sciences offers degree programs in Behavioral Neuroscience, Biochemistry, Biology, Earth and Environmental Science, and Molecular Biology. The P. C. Rossin College of Engineering and Applied Science offers a degree program in Bioengineering. Refer to the catalog entries below for complete descriptions.

Courses related to life science interest can be found under the catalog entries above as well as in other departments, including Chemical Engineering, Chemistry, Mathematics, Physics, Psychology, and Sociology and Anthropology.

Business

The designation of "business" refers to general business courses.

Undergraduate Courses

BUS 1. Introduction to Business (3)

An introduction to business, emphasizing critical issues impacting the business world, such as globalization, technology, ethics, and diversity. Provides an overview of the various functional areas of business and how they fit together. Stresses experiential learning and develops teambuilding skills. Strengthens written and oral communications skills. Provides an introduction to career opportunities and curriculum choices in business and economics. Course is offered only in the fall and is open only to College of Business and Economics freshmen.

BUS 05. Values Based Decision Making for Business (1)

An introduction to the foundations of business integrity. The role of individual decisions and ethics in business is explored. Students evaluate cases and ethical issues they are likely to face in business. Covers fundamentals of corporate governance and cases in governance failures such as WorldCom and Tyco. Social responsibility, ethical business leaders, and current topics in business ethics are addressed. Class dialog is emphasized along with reflective writing. Open only to CBE first year students. Prerequisite: BUS 01.

BUS 173. NonMajor Summer Internship (1)

CBE internships expose students to the business world, enriching their understanding of ideas and problems encountered in their business courses. This course is available summers and open to students in the College of Business & Economics and those in the following programs: CSB, IBE, and Business Minor. Students are evaluated on a directed writing assignment and on a detailed evaluation provided by the work supervisor. A minimum of 150 hours of work must be completed in the internship, and verified by work supervisor. Course registration and related arrangements must be made in advance of the work experience. This course does not satisfy any major requirements. Prerequisite: completion of a minimum of 24 college credits.

BUS 211. Integrated Product Development (IPD) 1 (3) spring

Business, engineering and design art students work in crossdisciplinary teams of 46 students on conceptual design including marketing, financial and economic planning, economic and technical feasibility of new product concepts. Teams work on industrial projects with faculty advisors. Oral presentations and written reports. Prerequisite: Junior standing in business, economics, arts or engineering.

BUS 212. Integrated Product Development (IPD) 2 (2) fall

Business, engineering, and design arts students work in cross disciplinary teams of 46 students on the detailed design including fabrication and testing of a prototype of the new product designed in IPD course 1. Additional deliverables include a detailed production plan, marketing plan, detailed basecase financial models, project and product portfolio. Teams work on industrial projects with faculty advisors. Oral presentations and written reports. Prerequisite: Bus 211/ENGR 211.

Bus 347. Practicum in Real Estate I (2) fall

This course is an interdisciplinary study of the creation of value in commercial real estate. Organized into groups, with each group assigned a different subject commercial real property, the class engages in the study of the physical and locational characteristics of commercial real estate as they relate to value including: property history; architecture; physical attributes that add to or detract from value; tenant mix; the immediate neighborhood environment; and, the specific market in which the real property competes for tenants. Each group submits a written report of their findings and produces a 10minute video documentary on their subject property. Prerequisites: Permission of the instructor. Students enrolling in this course must also commit to enrolling in the followon course Bus 348 Practicum in Real Estate II.

Bus 348. Practicum in Real Estate II (2) spring

This course is a continuation of the interdisciplinary study of the creation of value in commercial real estate begun in Bus 347 Practicum in Real Estate I. Organized into groups, with each group continuing with the subject commercial real property assigned to them in Bus 347, the class engages in the study of the market and financial characteristics of commercial real estate as they relate to value through: a financial analysis of the market in which their property is located to include market rents, market vacancy rates and market absorption rates; and, financial analysis of the subject property to include both historical results, and pro forma estimates of revenues, expenses, cash flow and residual value. Each group also studies the financial characteristics of comparable properties. The course culminates in an endofsemester written and oral presentation by each group before a panel of academic and practitioner judges. The group judged to have performed the most outstanding analysis is awarded a cash prize. Prerequisites: Bus 347 Practicum in Real Estate I.

Business Minor

Program Admission Requirements: Each spring, 80 students will be accepted into the business minor program for the following fall. Applications to the program will be made by students and submitted to the program director by the first Monday in March. An admissions committee comprised of the business minor program director, associate dean for the undergraduate CBE programs, and the business minor curriculum committee will make admission decisions based on G.P.A., experience, and interest in pursuing business opportunities upon graduation from Lehigh (to be evaluated on the basis of a written essay). Students will be notified of admissions decisions prior to registration for the fall semester. Entrance into business minor classes will be controlled by restricted overrides by the director of business minor program. The Director of the Business Minor program is Geraldo M. Vasconcellos, Allen DuBois Distinguished Professor of Finance & Economics (gmv0@lehigh.edu). Professor Vasconcellos' office is in the Rauch Business Center, Room 320.

Business Minor Courses

BUS 125. Behavioral Skills Workshop (1) fall

BUS 125 is a course that will have as its aim to equip students to work with others in a business setting in making business decisions. The focus of the class will be on effective decision making and will include such topics as group and team decision making, conflict resolution and negotiation, ethical decision making, and creative problem solving. This course will be offered as a series of intensive workshops in the fall semester and will heavily focus on experiential learning. Prerequisite: ECO 1. Corequisite: BUS 126.

BUS 126. Information Analysis and Financial Decision Making I (3) fall

An integrated introduction to business, accounting and finance. Students are introduced to the goals, people and activities of business, before focusing on the fundamental elements of accounting and finance, including financial statement construction and analysis, time value of money, financing and investing with equity and debt, and the impact of various operating decisions on business. Experiential learning, and development of team/communication skills, are encouraged through portfolio simulation and financial analysis projects. Prerequisite: ECO 1. Corequisite: BUS 125.

BUS 127. Information Analysis and Financial Decision Making II (3) spring

This course builds upon the foundational teachings of BUS 126 through examination of topics in portfolio management, capital investment decision making, business planning, analysis and reporting, and various specialized topics such as: entrepreneurship, business law, ethics, internal control systems, and Ebusiness. Experiential learning, and development of team/communication skills, are encouraged through group projects and guest speakers. Prerequisite: BUS 126.

BUS 225. Developing, Producing, and Marketing Products and Services I (3) fall

Introduction to the key elements in the marketing framework of a corporation. Focus on defining marketing, analyzing the market and competitors, developing effective marketing strategies, segmenting the market, creating customer value, satisfaction, and loyalty, analyzing consumer and business markets, creating brand equity, and managing an effective marketing program to deliver the right products and services to the right audience at the right place at the right price and the right time. Emphasis on business writing skills. Experiential learning through the development of a product or service marketing plan. Prerequisite: BUS 127.

BUS 226. Developing, Producing, and Marketing Products and Services II (3) spring

This course extends the marketing management principles initiated in BUS 225 with the creation, development, and delivery of new product ideas to the marketplace. Comprehensive overview of the new product development process, including how to develop an effective development strategy, manage crossfunctional teams across the organization, generate and evaluate concepts, manage the technical development of a product, develop the marketing plan, and manage the financial aspects of a project. As product innovation is a multidisciplinary field, this course, while focusing on marketing's role in product innovation, relies heavily on techniques that encompass engineering, research and development, management, production, and design. Emphasis on business writing skills and creativity. Experiential learning through the implementation of a new product idea and the performance assessment of both the supporting marketing and business plan. Prerequisite: BUS 225.

BUS 326. Business Strategy (1 credit hour. Spring.)

Business Strategy is a capstone course covering total enterprise problems in determination, execution, and control within a global setting. The course integrates the theories of production, marketing, finance and organization and provides an opportunity to study the function of higher level management as related to the total business environment through a teambased business simulation. Students will develop a business strategy and make decisions that impact performance metrics of the firm. Corequisite: BUS 226.

Business Information Systems

Program director. Catherine M. Ridings, Ph.D. (Drexel), associate professor management

Program faculty. Susan A. Sherer, Ph.D. (Pennsylvania) Kenan professor of information technology management and chair management; James A. Hall, Ph.D. (Oklahoma State), associate professor accounting; Lin Lin, Ph.D. (Arizona), assistant professor management; Yuliang Yao, Ph.D. (Maryland), assistant professor management; Chitra Nayar, M.B.A. (Iowa), lecturer; Dennis S. Praedin, B.A. (Muhlenberg); adjunct professor

Business information systems serve as a conduit for business change and they are the heart of today's business model. Our diverse faculty and contemporary curriculum is targeted at preparing our students to play a vital, valueadded role in today's rapidly changing business information environment.

Beyond understanding the key prerequisite technical skills, students will learn how businesses can leverage information technology and business information systems in conjunction with various management techniques in order to meet corporate tactical and strategic goals. By being introduced to the spectrum of today's leading technologies, students will understand the business implications and opportunities addressed in today's global economy.

The business information systems field is vibrant and exciting. There are a broad range of employment opportunities. Successful completion of the BIS program would invite students to pursue a wide range of career opportunities, including careers as a systems analyst/designer, information systems manager, information systems project manager, and information systems consultant.

The Business Information Systems major requires five (5) courses and two (2) electives beyond the core requirements of the College of Business and Economics. Students are required to take BIS 111, Introduction to Information Systems, as part of the business and economics core. Other courses are as follows:

Required Courses (5):

BIS 15 Business Application Programming (4) or
CSE 17 Structured Programming and Data Structures (4)
BIS 311 Managing Information Systems Analysis and Design (3)
BIS 324 Business Data Management (3)
BIS 333 Business Data Communications (3)
BIS 350 Project Management in IS (3)

Elective Courses (Choose 2):

ACCT 311 Accounting Information Systems (3)
BIS 331 Electronic Commerce (3)
BIS 342 Ebusiness Enterprise Applications (3)
BIS 372* Special Topics in Information Systems (3)
BIS 360 BIS Practicum (3) or
CSB 312 Design of Integrated Business Applications I (3)

*Courses focusing on different applications of IS in business, including: Data Warehousing and Mining, HR Applications in IS, Numerical Methods of Business Decisions, etc. Consult Professor Ridings for other related courses.

Undergraduate Courses

BIS 15. Business Application Programming (4)

Design, coding, and testing of business applications in a high level, objectoriented computer programming language. The course focuses on developing competence in the computer language by writing programs to solve business focused problems. Methods, classes, objects, control structures, arrays, string manipulation, graphics, graphical user interfaces, and webbased applets will be covered. Some previous experience with programming helpful but not required. Handson exercises will be included, taught in the computer lab.

BIS 111. Introduction to Information Systems (3)

This course examines the fundamental role of information systems in supporting and managing all business functions and enabling firms to compete effectively. Both technical and managerial aspects of information systems are introduced. The course integrates technical infrastructure, database concepts, management decisionmaking, and business process issues critical to the understanding of operational and strategic information systems. It introduces business applications that support accounting, finance, supply chain management, and marketing. Prerequisite: Excel competency.

BIS 311. Managing Information Systems Analysis and Design (3)

This course focuses on managing the requirements analysis and system design methodology and techniques for business information systems. Students learn current methods and techniques for system requirement analysis as well as system design, and apply them to real world projects. It covers cost benefit analysis and risk management of business systems development, JAD and structured walkthroughs, structured and object oriented methodologies, and software package evaluation. It emphasizes the factors for effective communication and integration with users and user systems and encourages interpersonal skill development with client users, team members, and others associated with development, operation, and maintenance of the system. Prerequisite: BIS 111 or consent of instructor.

BIS 324. Business Data Management (3)

This course covers the fundamentals of database management systems (DBMS), including database development, processing, logical and physical design, access, implementation and administration. Students will gain extensive experience in developing data models, creating relational databases, and formulating and executing complex queries. The focus in the course will be on analyzing the connections between data and business organizational information needs and decisions, and understanding the principles of managing organizational data. The course includes a project with handson experience with a large scale database and SQL. Prerequisite: BIS 311.

BIS 331. (MKT 331) Electronic Commerce (3)

This course covers how businesses and consumers use the Internet to exchange information and complete transactions. Both theoretical concepts and practical skills will be addressed with the scope of the class. Topics include advertising and marketing, e-commerce business and revenue models, online consumer behavior, web site design issues, Internet security, electronic payments, infrastructure issues, privacy issues, and overall electronic commerce strategy. Students will get handson experience designing e-commerce websites using web authoring software. Prerequisite: BIS 111, MKT 111 or consent of instructor.

BIS 333. Business Data Communications (3)

This course covers modern data communication technologies and how they are used in business. It provides an exposure to current and emerging networking and telecommunications technologies, introduces software and hardware fundamentals for various computer/network architectures, and provides an understanding of the business context of these technologies. Students will learn how to evaluate, select, and implement different communication options within an organization. The course emphasizes the business context of data communication technologies. Prerequisite: BIS 311.

BIS 342. (SCM 342) eBusiness Enterprise Applications (3)

Introduction to the implications of key information technologies used within and across businesses to conduct ebusiness. The course covers the functionality of various enterprise applications and their integration: customer relationship management, enterprise resource planning, supply chain management, supplier relationship management, data warehousing and mining, business intelligence, and product lifecycle management. Prerequisites: BIS 111 or consent of the instructor.

BIS 350. Project Management (3)

Key processes and tenets of project management including scope, time, cost, quality, human resources, communications, risk, procurement, and integration management. Both technical and behavioral aspects of project management are applied within the context of either IS management, HR management, Supply Chain Process Management, Small Business Management. Topics include: expectations management, change management and consulting engagement management. Introduces both software project monitoring tools and project team collaboration techniques and tools. Prerequisites: completion of all other courses in either BIS or Management major.

BIS 360. Business Information Systems Practicum (3)

The business information systems practicum provides an opportunity for students to work on an intensive consulting engagement with a business. Students work with client firms on individual or team projects, which focus on information systems activities such as developing requirements, designing, and implementing systems. Students complete written reports and make formal presentations to clients. May not be taken concurrently with MGT 311. Prerequisites: Junior standing in the College of Business and Economics.

BIS 371. Directed Readings (1-3)

Readings and research information systems; designed for superior students who have special interest in some topic(s) not covered by the regularly scheduled courses. Written term paper(s) required. May be repeated. Prerequisite: preparation in information systems acceptable to program coordinator.

BIS 372. Special Topics in Information Systems (1-3)

Special problems and issues in information systems for which no regularly scheduled course work exists. When offered as group study, coverage varies according to interests of the instructor and students. May be repeated. Prerequisite: preparation in information systems acceptable to program coordinator.

BIS 373. Business Information Systems Internship (1-3)

Based on a student's work experience, a sponsoring faculty member shall direct readings, projects, and other assignmentsincluding a "capstone report." It should be noted that the work experience (at least 80 hours per credit), by itself, is not the basis for academic credit. The faculty directed activity must be provided concurrent with the work. Course registration and related arrangements, including designating a sponsoring faculty member, must be made in advance of the work engagement. This course must be taken Pass/Fail, is not repeatable and cannot be used to satisfy BIS major or minor requirements. Prerequisites: BIS 311, declaration of a BIS major or minor, junior standing, and department approval.

Course descriptions for the College of Business and Economics graduate courses can be found in this section (Section V) under the heading of Business and Economics Graduate Courses.

Business Information Systems Minor

This minor provides an overview of the major technical functions in IS, such as design of systems and the development and management of databases. In addition, the student explores the applications of IS to business problems in either the e-commerce or ebusiness context. This minor is available only to students with a declared major in the College of Business and Economics.

Program of Studies: The BIS minor consists of 3 courses equaling 9 credit hours. These credit hours consist of the following courses:

Required Courses:

• BIS 311 Managing Information Systems Analysis and Design (3)
• BIS 324 Business Data Management (3)

Choice of either:

• BIS 331 Electronic Commerce (3) or
• BIS 342 E-Business Enterprise Applications (3)

Business and Economics Graduate Courses

MBA Prerequisites

GBUS 401. Financial Reporting for Managers and Investors (3)

Corporate financial reporting under Generally Accepted Accounting Principles. Analysis and interpretation of financial statements: accrual accounting, balance sheet valuation, income determination and cash flow analysis. Profit manipulation, window dressing and "creative accounting" through accounting policy choices. Fraudulent financial reporting, uses and limitations of accounting information. Accounting information as a tool for strategic decision making.

ECO 401. Basic Statistics for Business and Economics (3)

Descriptive statistics, probability and probability distributions, estimation, hypothesis testing, correlation and regression, chisquare analysis and analysis of variance. Computer applications.

MBA Program Core Courses

MBA 401. Introduction to the Organization and its Environment (2)

An MBA core course designed to provide a thorough understanding of business organizations by examining strategies middle and senior managers use to create and sustain organizational competitive advantage. The course examines the organization from an overall perspective within the context of the firm's internal and external environment. The second aspect of this course deals with the ability to communicate effectively in today's business and professional environment. Students will examine and practice the written and verbal communications strategies and skills that are essential to their success in business.

MBA 402. Managing Financial and Physical Resources (4)

An MBA core course designed to integrate financial and managerial concepts into operations decisions. Disciplines of accounting, finance and economics are combined to provide substantive foundations for discussing and analyzing data. Implications of analysis are applied to facilitate decisionmaking in other areas such as marketing, operations (manufacturing, logistics and engineering), human resources, information technology and general management. The major learning objectives will be applied through a series of "living" cases that are centered on analyzing historical financial performance, preparing a business plan, and valuing a business. Prerequisites: MBA 401, GBUS 401 or equivalent.

MBA 403. Managing Information (4)

An MBA core course dealing with concepts and methods involved in the collection, organization and dissemination of information that helps managers make operational and strategic decisions. The course also deals with attributes of information and examines enterprisewide impacts of local decisions. Revenue, cost, time and qualitybased information are accorded equal emphasis, while students are exposed to alternative evaluation methods for decisions related to different parts of the value chain. Topics include: activitybased costing; activitybased management; transaction analysis; operational and strategic decisions such as outsourcing, design partnerships, etc; investment analysis for short lifecycle investments; evaluation of uncertainty, risk and ambiguity; metrics development; compensation policies; segment evaluation methods; target costing and functional analysis; quality function deployment; total cost of ownership; and transfer pricing. In addition, the course deals with: information technology enablers which allow firms to improve value delivered to customers; and evaluation and management of emerging forms of Cooperation, such as joint ventures and project based strategic alliances. Prerequisites: MBA 401, GBUS 401 and ECO 401 or equivalents.

MBA 404. Managing Products and Services (4)

An MBA core course focusing on the management of products and services within a firm's value chain. The course addresses exceeding customer expectations, establishing total quality as the core foundation, developing a strong customer focus, creating value through supply chain management, developing new products for competitive advantage, matching aggregate supply with customer demand, and designing market channels and influencing customers. Prerequisite: MBA 401.

MBA 405. Managing People (4)

An MBA core course that examines how effective organizations are created, maintained, and improved. The course will focus on how good people are attracted to an organization and how to make them productive. Topics include: organizational design, job design, staffing, training and development, performance, teams, influence, diversity, change, ethical decisionmaking and current people issues facing today's organizations. The course includes a comprehensive simulation (to be conducted on a Saturday during the semester) and a group project which allows students to apply the principles and concepts covered in the course. Prerequisite: MBA 401.

MBA 406. Integrative Experience (3)

An MBA course where students apply the body of knowledge acquired in MBA 401 through 405 through a simulation, case presentations and the cross core project. This course places an emphasis on strategic management and takes the point of view of the general manager to view the organization from an overall perspective in the context of the firm's internal and external environment. In doing so, students examine historical perspectives, contemporary theories, and practical applications all in the spirit of helping them develop a broad understanding of strategic management issues and solutions. By combining highlevel class discussions, case analyses, a computer simulation competition and the crosscore project this course exposes students to rigorous theoretical analysis while providing handson, simulated real world business experiences. Prerequisites: MBA 401, MBA 402, MBA 403, MBA 404, MBA 405.

Accounting Electives

GBUS 413. Advanced Management Accounting (3)

Issues in management accounting including activitybased costing, activitybased management, strategic cost management, theory of constraints, advanced manufacturing technologies, cost of quality and lifecycle costing. Readings and cases. Prerequisite: MBA 403 or a course in cost accounting.

GBUS 414. Financial Statement Analysis and Interpretation (3)

This course focuses on analysis of financial statements. It develops the skills necessary to interpret and use financial statement information effectively to assess profitability and risk and is intended for individuals likely to become intensive users of financial accounting information. Requirements include readings, case studies, presentations, and written analysis of actual financial statements. Prerequisite: GBUS 401 and MBA 402 or permission of the instructor.

GBUS 437. Federal Taxation and Business Decisions (3)

Impact of federal taxation on the structure and timing of business decisions. Problemsolving methods and research techniques from a managerial perspective. Prerequisite: ACCT 307.

Finance Electives

GBUS 419. Financial Management (3)

An intermediate level course in corporate finance. Coverage includes capital budgeting techniques including real options, decision tree analysis, risk analysis, advanced cost of capital theories, capital structure theory, dividend policy, working capital management, mergers and acquisitions, restructuring, and bankruptcies. The course emphasizes both theory and practice through lectures, cases, and financial modeling exercises. Prerequisite: MBA 402 or equivalent background. Students not possessing the relevant prerequisites must obtain waivers from the designated finance faculty representative.

GBUS 420. Investments (3)

A survey course in investments. Overview of financial institutions and markets involved in the issuance and trading of securities. Emphasis on valuation and risk assessment of fixed income and equity securities. Construction of optimal portfolios and examination of performance measures. Prerequisite: MBA 402 or equivalent background. Students not possessing the relevant prerequisites must obtain waivers from the designated finance faculty representative.

GBUS 421. Advanced Investments (3)

Advanced topics relating to valuation/security analysis and portfolio/risk management. Prerequisites: GBUS 420 or designated finance faculty representative approval.

GBUS 422. Derivatives and Risk Management (3)

The theory and application of a variety of derivative instruments (options, futures contracts, etc.) used in corporation finance and the financial services industry. The focus is on the risk management application vs. a rigorous development of option pricing theory and similar topics. Prerequisites: GBUS 420, or Designated Finance Faculty Representative Approval.

GBUS 424. Advanced Topics in Financial Management: (description to change each time course is offered) (3)

Advanced topics relating to specific areas of corporate finance such as: theoretical and empirical examination of recent developments in financial management; asset valuation and capital budgeting including the role of uncertainty, imprecise forecasts, risk preferences, inflation, market conditions, and the global marketplace; working capital management, leasing, mergers, and financing. The course content may vary between instructors and over time. Prerequisite: GBUS 419 or designated finance faculty representative approval.

GBUS 425. Real Estate Financing and Investing (3)

An upperlevel course in modern real estate financing techniques from the perspectives of both the borrower and the lender. Subject matter encompasses the following areas: The principles of financing decisions; financing methods and techniques; institutional sources of funds for real estate; and real estate financing decisions. Prerequisites: GBUS 420, or designated finance faculty representative approval.

GBUS 426. Financial Markets and Institutions (3)

Functions and portfolios of financial intermediaries. Sectional demand and supply of funds, nature and role of interest rates, term structure and forecasting, impact of inflation and regulations on financial intermediaries and markets, and current developments in the financial system. Management of assets and liabilities within the U.S. financial institution's legal and economic constraints. Prerequisite: GBUS 420, or designated finance faculty representative approval.

GBUS 431. Quantitative Finance (3)

Relationship of quantitative models to financial theory and applications. Capital budgeting, portfolio selection, security evaluation, cash management, inventory policy and credit analysis. Prerequisite: GBUS 419 or designated finance faculty approval.

Management Electives

GBUS 440. Human Resource Management (3)

A survey of personnel management activities in organizations. Topics include human resource planning, recruitment, selection, equal employment opportunity, performance appraisal, compensation, career planning, safety and health, and quality of work life issues. Course consists of lectures, discussion, and case analysis.

GBUS 442. Seminar in Management Consulting (3)

A study of consulting practices in general and their application to small business. Processes include a field study/counseling service to a local business. Emphasis is on the identification and analysis of multidisciplinary problems and opportunities and the implementation of recommendations. Prerequisites: completion of MBA background courses (or equivalent) and permission of the instructor.

GBUS 444. Managerial Communication Skills (3)

Organization, style and strategy of language to inform, direct and persuade. Application of writing, reading, speaking and listening skills to managerial problems. Case studies.

GBUS 445. Labor-Management Administration (3)

A study of the U.S. system of industrial relations, including the evolution and present status of labor law; union organizing efforts; the strategy of negotiations; the substantive provisions of collective bargaining and the administration of collective agreements. Also considered is the role of unions in the implementation of programs for employee selfmanagement and other workplace innovations.

GBUS 446. Commercial Potential Assessment (3)

A study of the process of bringing an invention to market with emphasis on commercial potential. Industrial analysis, competitor intelligence and strategic issues will be emphasized along with the development of market strategy and an overall business plan. Extensive research including data base searches will be included. Instructor permission required.

GBUS 447. Negotiation (3 credits)

The class examines the behavioral foundations of the negotiation process. Topics include: The negotiation process, negotiation planning, power in negotiations, communications in negotiations, tactics, concepts of winwin and winlose, social styles, individual and team negotiations, ethical considerations, cultural differences, negotiating in sole source (customer) situations, using third parties. The concepts will be exposed through both lectures and simulations.

GBUS 450. Strategic Supply Management (3)

A survey course designed to introduce the MBA/MSE student to the vital role played by supply management in achieving overall effectiveness for the firm in today's global economy. The course starts by examining the traditional purchasing process and then moves on to an examination of the evolution of purchasing into supply management and, finally, to the role purchasing plays in improving effectiveness of the entire value chain. Course consists of lectures, discussion and case analysis.

GBUS 451. Analytical Methods in Management (3)

Application of management science methods to industrial and commercial problems. Scientific method, decision theory, linear programming, inventory control, regression analysis, forecasting, simulation, and related areas are examined in the context of accounting, finance, marketing and manufacturing.

GBUS 453. Transportation and Logistics Management (3)

The control of physical distribution and inventories; the flow of information, products and cash through the integrated supply chain.

GBUS 454. E-Commerce and Marketing Strategy (3)

Impact of e-commerce technologies on firms, industries, and markets. Covers the technologies used in e-commerce, changes in organization structure, industry and behavior, and sales and marketing strategies such as attracting visitors to websites, promotion, distribution, service, pricing, branding, advertising, consumer behavior, measuring effectiveness, societal effects, disintermediation, reintermediation, and strategy implementation. Prerequisite: MBA 403.

GBUS 455. E-Business Enterprise Applications (3)

Implications of key information technologies used within and across businesses to conduct ebusiness, including customer relationship management, enterprise resource planning, online ordering and inventory management, supply chain management, and e-procurement systems, data warehousing, data mining, intraextranets, and knowledge management. Prerequisite: MBA 403.

GBUS 456. Business Process Redesign with Information Systems (3)

Current topics on the principles, implementation and critical success factors of deploying information systems enabled quality management and process innovation within organizations. Techniques and tools used in implementing quality and process innovation from a managerial and practical perspective. Prerequisite: MBA 403.

GBUS 457. Managing the IS Resource (3)

The issues and management techniques involved in administering the information systems/resource activities in the organization. Management of IS professionals, development and management of project teams, user client relationships, managing vendors, emerging technologies and planning processes. Prerequisite: MBA 403.

GBUS 458. Strategic Information Systems (3)

Understanding the various types of computer based information systems and developing an ability to identify and exploit information technologies to gain competitive advantage, at the individual, group and organizational levels. Prerequisite: MBA 403.

GBUS 459. Survey of Project Management (3)

Provides an overview of the project management framework and knowledge areas. Covers the daytoday, handson problems of managing a project (defined as a temporary structure within a permanent organization, set up to achieve a specific objective). Areas covered will include: project integration, project scope, project planning and implementation, project control and evaluation, project cost and risk management, project resource management and organization, and project communication. Cases will be used to illustrate problems and the techniques to solves them. A basic project management software tool will be introduced and utilized in this course. This course is designed for MBA students who want a general exposure to project management concepts. This course may not be used in the Project Management Certificate Program.

Marketing Electives

GBUS 460. Strategic Marketing Management (3)

The course studies the management of contemporary organizations from the perspective of a marketing manager. While the course content addresses the activities required to maintain a strategic fit between an organization's environment and its particular set of objectives and resources, the central focus is on designing strategic marketing actions for various types of organizations. The course pedagogy emphasizes the application of marketing and other business principles through seminars, simulations, or case discussion.

GBUS 462. Pharmaceutical Marketing

The course provides an introduction and overview of the various healthcare system components as they relate to the pharmaceutical industry. This course will (1) focus on product decisions of the firm, requiring an occasional shift in focus from that of corporate management to that of operating managers of new product activities or established brands;A0(2) recognize the importance of marketing research as input to product decisions; (3) take a managerial orientation; (4) recognize the need to tailor product policy approaches to the characteristics of the decisionmaker and the firm. The course will be a mixture of lectures, discussions, case analyses, and group exercises. Prerequisites: Graduate students only.

GBUS 464. Business-to-Business Marketing (3)

This course focuses on marketing strategies and tactics in firms whose customers are other institutions, not individuals. Topics covered include organizational buying behavior, managing strategic buyerseller relationships, sales force deployment, communication strategies, and so on. Specific attention is given to the impact of information technology and globalization in the businesstobusiness context.

GBUS 465. Creating Breakthrough Innovations (3)

Most products and services either fail or do average business, but some are phenomenally successful. Such products and services that provide phenomenal financial returns and become market leaders can be called "Breakthrough Products and Services". The main objective of the course is to improve our understanding of the process of creating breakthrough products and services. It is accomplished by inclass discussions of cases, assignments, and the stateoftheart research work in academia and industry. The course concludes with a term paper that integrates the concepts learned from class discussions, reference books, and research papers and applies them to a real product. Prerequisites: Graduate student status plus two years of postgraduate work experience.

GBUS 466. Marketing Research and Analysis (3)

This course focuses on procedures for collecting and analyzing relevant information for informed decision making by managers. The process of identifying research questions, developing instruments for collecting information, appropriate interpretation of information, and appropriateness of research methods are some of the topics discussed in this course. The course focuses on the process of doing marketing research as well as the techniques for analyzing information. Discussion of concepts and cases, developing data collection instruments, and doing actual marketing research projects will form the key elements of this course.

GBUS 470. Marketing Communications Strategies (3)

This course focuses on how various elements of communications are integrated to achieve various organizational objectives. In addition to the traditional communication media such as advertising and point of purchase media, emphasis will also be placed on new media and strategies made possible due to the advances in technology. The course will involve discussion of concepts, case analysis and discussion, insights from practitioners, and group projects.

GBUS 471. Strategic Brand Management (3)

This course will focus on theories, models, and other tools to manage brands, products, and product lines. Specific attention will be focused on building, measuring, and managing brand equity. The course will be a mixture of lectures, discussions, case analyses, and group exercises. Prerequisite: MBA 404.

GBUS 472. Strategies for Services Marketing (3)

The course focuses on the challenges of marketing and managing services (whether in a manufacturing or service business) and discusses the development of strategies for addressing these challenges. The need for crossfunctional integration to provide effective service is stressed. Illustrative topics include service quality gap analysis, relationship between superior service and profitability, service encounter analysis, customer lifetime value analysis, services guarantees, and service demand and capacity management.

International Business Electives

GBUS 473 International Finance (3)

Consideration of problems arising from the risks associated with international investing and multinational corporation finance (currency, political, etc.). Focus is on

(a) investing in international market given the institutional constraints and differences between domestic markets, and (b) managerial issues relating to corporations, investors, and financial institutions. Prerequisites: GBUS 419, or designated finance faculty representative approval.

GBUS 474. Legal Aspects of International Business (3)

Various legal problems of engaging in business abroad, including contracts, technology transfer, property ownership, business organizations and labor, using a case and problemsolving approach.

GBUS 475. Global Marketing Strategies

The course is designed to provide a framework within which global marketing operation can be analyzed, understood, and undertaken. The course focuses on the issues that are being faced by firms in today's global marketplace, particularly those that are related to strategy formulation and implementation. The learning experience in this course is placed on global business decisionmaking, through the use of case studies, projects, and lectures.

GBUS 476. Globalization and Management of Technology (3)

Management of science and technology in the context of international business and the globalization of markets, competition and corporations. Management of global industrial R & D; technology-based global strategic alliances; global external technology sourcing, complex human resources and crosscultural issues; etc. Develops an appreciation of the scientific and technical capabilities available globally and the potential for global Cooperative and/or competition in this regard.

Management of Technology Electives

GBUS 481. Technology, Operations and Competitive Strategy (3)

Develops an understanding and appreciation of the interrelationships among technology, operations and the competitive strategy of the firm. Industry analysis and competitiveness; competitive strategy formulation and implementation; value chain analysis; operations strategy and technology strategy; operation's contributions to competitive advantages in cost, quality and variety and new product introduction.

GBUS 482. R, D & E Project Management (3)

Management of crossfunctional project teams for introducing technological innovations in the manufacturing and marketing of new products and services in a variety of industries.

GBUS 483. R & D Management (3)

Developing R&D programs to achieve strategic business objectives; selecting, staffing and managing R&D projects; and transferring research results to commercial functions.

GBUS 484. Science and Technology Policies and Institutions (3)

The science and technology institutional infrastructure and its relationships with management decisionmaking, including private, public (government) and quasipublic institutions; R&D, regulatory, and policy institutions; and U.S., foreign and international institutions.

GBUS 485. Diffusion and Implementations of Technology (3)

Classical macrostudy of adoption and diffusion of innovation, and managing the implementation/utilization/ application of new technology in the organization/corporate culture.

GBUS 486. Qualitative Research Methodology (3)

Study of techniques that describe, decode and translate social phenomena. Explores how interpretive researchers plan and conduct studies and present findings. Studies investigators' roles, data sources, observation methods, dataanalysis methods and trustworthiness of findings. A field research project is required.

GBUS 494. Field Projects (1-4)

The field projects course will provide MBA students with an opportunity to apply MBA concepts with an employer, corporate partner or other suitable organization. Students will work with a supervising professor and a corporate representative on a project designed by the student. Students must prepare a written proposal for the project including the expected outcomes and an estimate of the hours required for completion. Students will present their proposal to a faculty member of their choice for approval. The academic rigor and time required to complete the project will determine the number of credits earned.

VentureSeries (Corporate Entrepreneurship)

GBEN 401. The Business Plan I: Strategic Considerations (2)

This course is first of a twopart sequence that focuses on the initial steps necessary to design and build a highimpact business plan for the startup company or new enterprise within an existing firm. The development process is integrative, complex, and timeconsuming for the entrepreneur. Foundation or strategiclevel issues that impact the formation and growth of the new enterprise are addressed. The goal in this first phase is to complete various sections of the business plan that deal with market opportunity, industry trends and developments, company positioning, competitive advantage, and core competencies. This course is projectoriented and makes extensive use of oneonone instruction between class meetings. Students identify a market opportunity, develop the product/service offering, target potential customers and users, assess market demand, analyze market penetration, and determine the revenue potential of the new venture. 2 Credits

GBEN 402. The Business Plan II: Operating Strategies and Implementation (2)

This course is the second of a twopart sequence that focuses on the final steps necessary to complete the business plan. This phase concentrates on designing the appropriate operational framework and business processes, including technology and infrastructure, which are required to successfully launch the new enterprise. The business plan must also demonstrate that the venture will have strong leadership and a capable management team to deal with uncertainty and drive results. Finally, the business plan must incorporate detailed financial forecasts and financing methods, and should address equity valuation and investor exit strategies. Like its predecessor, this course is projectoriented and makes extensive use of oneonone instruction between class meetings. Additional emphasis is placed on developing an effective format and packaging of the written document. 2 Credits

GBEN 403. Anatomy of Entrepreneurship: Startups and Established Companies (1)

This interactive seminar focuses on understanding the true meaning of entrepreneurship. The new venture opportunity is profiled from the perspective of the individual entrepreneur who is starting a business and embarking on a new career path involving high risk and reward. Different entrepreneurial management styles are analyzed and highlighted. Course emphasis is also placed on managing innovation and creativity in a corporate environment. Successful implementation of entrepreneurial activities for the large company makes special demands on management to promote discovery and create internal stakeholders. Both startups and established companies are placed under the microscope through guest speakers, panel discussion, selected readings, and case analysis. 1 Credit

GBEN 404. Market Opportunity: Targeting Strategies and Selling Tactics (1)

The focal point of any business plan is identifying and understanding the target customer that will be served. The product/service offering must have strong buyer appeal and capture immediate attention in the marketplace. The need to rapidly penetrate a market demands that a marketing mix be designed, built, and implemented in a manner that leads to differentiation and superior positioning. Maximizing marketing firepower with severely limited financial and organizational resources is a major challenge that confronts today's entrepreneurs. Market segmentation strategies, the target marketing process, forming market alliances, and managing the selling process are viewed from the perspective of seed and early stage ventures. 1 Credit

GBEN 405. Intellectual Property: Management and Valuation (1)

New technologies create new markets and new venture possibilities. Their discovery and success rate, along with the ability of an enterprise to leverage these assets in markets, depends on how the firm views and manages its investment in intellectual property. Obtaining the necessary legal protection of intellectual property can also serve as an effective barrier to entry and may be a source of competitive advantage. This seminar focuses on the strategic management of intellectual property as a commercial enterprise, covers methods of valuation, and examines various accounting and legal issues that must be considered in strategiclevel decision making. 1 Credit

GBEN 406. Performing a Business Enterprise Audit: Developing an Industry Perspective (1)

New ventures must position themselves for longterm growth and market development. Entrepreneurs create enterprises, define their organizations, and build business models based on changes in technology, government regulation, demographics, and shifts in other exogenous variables. A strategy must be crafted that is sustainable over the long run. Success or failure is often predicated on market cycles, market saturation, supply/demand imbalances and other forces that are not controllable. This seminar places emphasis on assessing the market potential and valuation of startups from an industry or macroperspective, particularly from the view of an outside investor. It also focuses on how to gather and make effective use of competitive intelligence. 1 Credit

GBEN 407. Processes and Infrastructure: Creating Production and Delivery (1)

This course provides an overview of the internal capabilities and the process and technology platform required to fully operationalize the business plan. Critical business activities and functions are dissected, such as establishing needed backend procurement, production, and distribution services that focus on supply chain dynamics and management; determining the scope of frontend call center and e-commerce activities; managing logistics; and utilizing information systems and webbased solutions that effectively link customers, elements of the supply chain, and employees. These topics are explored from the perspective of the startup and emerging company as well as the large corporation engaged in new venture creation. 1 Credit

GBEN 408. The New Venture Organization: Management, Design, and Governance (1)

Managing a new enterprise presents unique and difficult challenges for its leadership. Expanding workloads and the increased complexity of tasks resulting from the rapid and sustained growth of the business create the need for a smooth transition from entrepreneurialstyle management to professional management. Timing is critical, and for many startups it is not an easy bridge to cross. This course dissects the design and characteristics of small organizations, and the need to correctly align structure with strategy. It also considers how entrepreneurial activities should be seeded, managed, organized, and executed within the context of an established company. Under scrutiny are the heavy demands placed upon entrepreneurs and corporate managers to effectively lead and manage under highly uncertain conditions where change is a constant. Additional course emphasis is placed on comprehending the critical role that boards of directors play for startup companies. 1 Credit

GBEN 409. Financial Forecasting: Developing Pro Forma Financial Statements (1)

No business plan would be complete without providing detailed financial projections and identifying the key assumptions that help shape the numbers. The financial translation of business models is expressed through pro forma income statements, balance sheets, and sources and uses of funds. Having this information allows management, investors, and lenders to measure and evaluate future financial performance. This exercise also establishes the capitalization required to launch the venture, support operations, and meet interim goals as the enterprise progresses through the beginning stages of its development. Course emphasis is placed on the use of forecasting methods and breakeven analysis, working capital and cash flow management, and identification of accounting and financial issues that impact on profit measurement and financial risk. 1 Credit

GBEN 410. Financing StartUps: Seeking Outside Venture Capital (1)

This course provides an overview of the venture capital market, examines the nature and role of the venture capitalist, and analyzes whether and how venture capital financing may be the preferred approach in raising outside capital. Venture deals are closely examined in terms of types of equity instrument, methods of valuation, milestones and staged release of funds, special provisions that may include antidilution measures and other protective arrangements, and developing term sheets. Emphasis is also given to dissecting the process and criteria used to seek and attract venture capitalists, including angel investors. Various scenarios and tradeoffs are covered in this intensive course. 1 Credit

GBEN 411. Establishing Credit Facilities: AssetBased and Cash Flow Financing (1)

Borrowing from a commercial bank or a credit intermediary can provide outside funding for working capital and equipment purchases in many situations. For seed and early stage firms, attention is often given to assetbased lending programs that make use of first liens on accounts receivable and inventory or fixed assets to provide added legal protection to creditors. For later stage firms, traditional lineofcredit financing may be feasible and desirable from a cash flow standpoint. Various borrowing alternatives, including leasing, are covered in this course along with covenants and restrictions that often apply. Government loan programs, especially those of the Small Business Administration, are also given emphasis.1 Credit

GBEN 412. Developing Exit Strategies: Concepts and Approaches (1)

Sophisticated equity investors require that an exit or harvest plan be developed and that it be viable and capable of being executed within the foreseeable future. Venture capitalists and angel investors anticipate their future departure and a positive financial outcome at the very point the deal is struck in the present. Various planned and unplanned exit strategies are analyzed in this course which include: an initial public offering, offering the business for sale, merging with another company, franchising, acquisition of shares by some investors, or liquidation of the business. Valuation methods, financial and tax implications, and due diligence are also examined. 1 Credit

GBEN 413. Integrative Experience/New Venture Internship (1-4)

Only students enrolled in the Entrepreneurial concentration may elect one of these handson, projectorientated courses. Integrative Experience must meet the requirements of formal independent study and involve a new venture situation with a startup or existing company. Students employed in a New Venture Internship may also qualify for course credit if the same requirements are satisfied.

Project Management Electives

Must be taken as sequenced courses and may not be taken individually.

PMGT 401. Project Management: Course Framework & Project Leader Assessment (1)

Introduction to the Project Management Certification Course; syllabus, requirements and deliverables. Students will become acquainted with: the terminology, nine knowledge areas, relationships to other disciplines, project management context and processes. Introduction to the logistical vehicles for course delivery and the tools to be used. Students will also assess themselves as project leaders and explore project leader competencies, roles, responsibilities and stakeholder relationships.

PMGT 402. Project Management: Skills and Abilities for Effective Leadership of Teams (1)

Students will enhance project team leadership skills, define the work environment of project teams, team selection, develop a team charter, clearly define the roles and responsibilities of all project team members, set team guidelines, learn methods to promote teamwork, understand the stages of development, and manage team dynamics. Additional skills covered: delegation, managing accountability without direct authority over project team members, managing dysfunctional teams, performance improvement, input to performance appraisals, rewards, recognitions, celebrations. Prerequisite: PMGT 401.

PMGT 403. Project Management: Initiating the Project and Planning Scope and Schedule (2)

Students will learn techniques for deciding whether to undertake a project and for planning project outcomes and schedules. The relationship of projects to organizational planning and budgeting, information and performance appraisals systems will be discussed. Approaches will be shared for identifying and classifying project stakeholders and designing and conducting a cost benefit analysis. How to define desired project outcomes clearly and completely and how to determine project work to be performed using decomposition and templates will be addressed. Students will learn how to develop a project charter, a scope statement, a Work Breakdown Structure, a WBS dictionary and a Linear Responsibility Chart. How to create a network diagram and analyze schedule possibilities using the Critical Path Method (CPM) and the Program Evaluation and Review Technique (PERT) will be explained. Fast tracking and crashing a schedule will also be explored. Displaying a schedule with a Gantt Chart, key events list and activities will be illustrated. How to support these activities using MS Project will be demonstrated. Prerequisites: PMGT 401, PMGT 402

PMGT 404. Project Management: Planning Resources, Communication, Quality and Risk Management (2)

In this course, students will learn how to estimate the needs for personnel and other types of projects resources, to develop a project budget and to plan for additional project support activities. Determining the type, amount and timing of resource needs will be emphasized. Approaches to resource leveling will be discussed. The different types of project costs will be explained. The use of analogous estimating, parametric modeling, bottomup estimating and computerized tools to estimate costs will be explored. Planning to ensure project quality and coordinate project communications will be will be addressed. Identifying, assessing, and preparing a plan to manage project risks will also be discussed. Planning for project procurement and associated solicitations will be explained. Students will learn how to develop resource matrices, loading charts and grafts and a project budget. How to support these activities using MS Project will be demonstrated. Prerequisites: PMGT 401, PMGT 402, PMGT 403

PMGT 405. Project Management: Project Leader Communications Expertise and Evaluating Team Performance (1)

The purpose of this weekend seminar is to strengthen the project leader's communication skills, changemanagement skills, conflict resolutions skills, and team evaluation skills. Focus areas will also include the following: understanding the art and science of effective listening, managing multiple expectations, communicating "bad news," and learning tools and techniques for project team evaluation. Prerequisites: PMGT 401, PMGT 402, PMGT 403, PMGT 404

PMGT 406. Project Management: Implementing and Managing Projects (2).

Students will learn techniques and processes to start and perform the actual project work. Suggestions for working successfully in a matrix management environment will be discussed. Information systems to track schedule performance, labor charges and project expenditures will be expressed. Developing escalation procedures to address project conflicts issues will be emphasized. Procedures for controlling labor and fund charges to a project will be introduced. Key project review and decision meetings will be identified. Planning and implementing quality assurance activities will be addressed. Planning for, awarding and administering contracts will be discussed. How to support these activities using MS Project will be demonstrated. Prerequisites: PMGT 401, PMGT 402, PMGT 403, PMGT 404, PMGT 405

PMGT 407. Project Management: Controlling Performance and Assessing Outcomes (2)

Students will learn how to monitor and control project activities in progress and how to bring a project to closure. Approaches for assessing project products and services produced will be explored. Techniques for evaluating schedule and cost performance will be introduced. Variance analysis and earned value analysis will be explained. Quality control and risk monitoring and control will be discussed. Change control systems and procedures will be explained. How to prepare focused progress reports and conduct effective project meetings will be discussed. Requirements for closing out contracts and procurements will be detailed. Obtaining user acceptance, closing labor and fund charge accounts and other administrative activities will be discussed. Designing and conducting a postproject review will be explored. How to support these activities using MS Project will be demonstrated. Prerequisites: PMGT 401, PMGT 402, PMGT 403, PMGT 404, PMGT 405, PMGT 406

PMGT 408. Project Management: Problem Solving, Decision Making and Ethics (1)

This 2day seminar focuses on developing problem solving and ethical decisionmaking skills. Students will learn to recognize project problems, frame the problem, assess risk, manage risk, plan contingencies, recognize the escalation points, and apply alternate methods. Students will also participate in ethical exercises to strengthen their ability to recognize ethical dilemmas and evaluate decisions. Prerequisites: PMGT 401, PMGT 402, PMGT 403, PMGT 404, PMGT 405, PMGT 406, PMGT 407

M. S. Core Courses

MACC 401. Professional Issues in Accounting - Negotiation (1)

This course examines the behavioral foundations of the negotiation process. Topics include planning, tactics, power, integrative and distributive bargaining, behavioral styles and individual and team negotiations. MACC 401, 402 and 403 are prerequisites to the balance of the MSAIA core course sequence. Open only to MSAIA students.

MACC 402. Professional Issues in Accounting - Case Analysis (1)

Introduces business case analysis. Cases will be dissected, analyzed and discussed. A range of business topics will be used to demonstrate the case method. MACC 401, 402 and 403 are prerequisites to the balance of the MSAIA core course sequence. Open only to MSAIA students.

MACC 403. Professional Issues in Accounting - Ethics (1)

Examines ethical issues as they relate to business. Through debate and case studies, students will be challenged to determine what are acceptable and ethical business practices, primarily in an international environment, and how these practices relate to the highly diverse elements that comprise today's complex, global enterprises. MACC 401, 402 and 403 are prerequisites to the balance of the MSAIA core course sequence. Open only to MSAIA students.

MACC 412. Information Systems Auditing (3)

Modern information technology auditing and impact of computer controls on operational efficiency and external auditing under SarbanesOxley Act. Focuses on key threats and audit procedures relating to operating systems, data management, systems development, electronic commerce, organization structure, computer center operations, Enterprise Resource Planning (ERP) systems, and revenue and expenditure cycles. Issues in fraud prevention and detection. Emphasizes data extraction software for auditing and integrates ACL and SAP into auditing scenarios. Prerequisites: Accounting 311, Acounting 320, MACC 401, 402 and 403.

MACC 413.The Corporate Financial Reporting Environment (3)

Uses theory and research results to study financial reporting's role in providing decisionuseful information to capital market participants. Topics include the financial reporting revolution, efficient markets theory and research, economic consequences and Positive Accounting Theory, conflict between owners and managers, executive compensation, earnings management, standardsetting, the FASB's conceptual framework, and International Financial Reporting Standards. Prerequisites: Accounting 316, MACC 401, 402 and 403.

MACC 420. Consulting Process and Practice in Professional Accounting (3)

Consulting and advisory processes relates to accounting firms and internal consultation in industry. Focuses on consulting process life cycle: gaining and retaining clients, developing proposals and engagement letters, defining client needs and diagnosing problems, collecting and analyzing data, documenting findings, developing solutions and recommendations, and managing projects. Uses case studies and outside speakers. Students complete a real life consulting project and present findings orally and in writing. Prerequisites: MACC 401, 402 and 403.

MACC 424. Corporate Governance and Business Risk (3)

Focuses on assurance and risk management services offered by public accounting firms. Integrating topics from accounting, auditing, ethics, economics, risk management, internal control, and business strategy, the course develops an indepth understanding of how corporate governance and business risk issues relate to assurance practice in today's postSarbanesOxley environment. Students complete an assurance and risk management engagement for a "reallife" smalltomedium size client. Prerequisite: MACC 401, 402 and 403, and MACC 412 or concurrent.

MACC 427. Analyzing Accounting Information for Management and Business Solutions (3)

Examines the interaction of accounting information, business models, financial analysis and information technology to resolve complex business problems. Topics include using control systems to guide business strategies, creating performance measurement systems, evaluating strategic profit performance, linking internal operations to external markets, and balancing profit, growth, management attention, earnings quality analysis and business valuation. Prerequisite: MACC core or concurrent; taken during the last semester of the program.

Economics

M.S. And Ph.D. Core Courses

ECO 402. Managerial Economics (3)

Application of economic and statistical analysis to managerial decisionmaking. Business and economics forecasting. Empirical estimation of demand, production and cost functions. Resource allocations and pricing strategies in various market structures. Decisions under risk and uncertainty. Government regulations of business. Cases. Prerequisite: Calculus and ECO 401 or equivalent.

ECO 411. History of Economic Thought (3)

Selected topics in the history of economic thought, with special attention to the origins of modern economic theory. Prerequisite: a graduate course in economic theory.

ECO 412. Mathematical Economics (3)

Applications of various mathematical techniques in the formation and development of economic concepts and theories. Prerequisite: consent of the chair.

ECO 413. Advanced Microeconomics Analysis (3)

A survey of methods of decisionmaking at the microeconomic level; price theory and econometric applications. Prerequisite: ECO 402 or equivalent.

ECO 414. Advanced Topics in Microeconomics (3)

Resource allocation and price determination. Theories of choice of consumers, firms, and resource owners under various market forms. Prerequisites: ECO 401 and ECO 413 or equivalents.

ECO 415. Econometrics I (3)

Computer applications of standard econometric techniques using regression analysis in a singleequation context. Discussion of problems of multicollinearity, heteroscedasticity and autocorrelation. An introduction to simultaneous equation models, identification and estimation problems. Prerequisite: ECO 401 or equivalent.

ECO 416. Econometric Theory (3)

Mathematical and statistical specification of economic models. Statistical estimation and tests of parameters in single and multiple equation models. Prediction and tests of structural changes. Prerequisites: ECO 401 (or equivalent) and calculus.

ECO 417. Advanced Macroeconomic Analysis (3)

Macroeconomic theory and policy. Emphasis on theoretical models and policy implications.

ECO 418. Advanced Topics in Macroeconomics (3)

Models of employment, income and growth in monetary economies. Policies for economic stability and growth. Prerequisite: ECO 417 or equivalent.

ECO 423 Real Options (3)

This is an introductory graduate level course in financial economics. It is intended for students with strong technical backgrounds who are comfortable with mathematical arguments. The course is divided into three main parts: deterministic finance, singleperiod uncertainty finance and options theory and its applications. Prerequisite: GBUS 420.

ECO 424 Advanced Numerical Methods (3)

This course focuses on techniques that apply directly to economic analysis. A particular emphasis is on problems in finance. The course teaches students how to use EXCEL macros and advanced VBA (the industry standard). It is designed for decision making in business settings.

Economics Electives

ECO 404. Technology, Trade and Economic Growth (1)

Overview of the role of technology in economic systems. Productivity and growth effects, relationships to industry structure, impacts on international trade and competitiveness. Prerequisite: intended to be taken concurrently with ECO 402.

ECO 423. Real Options (3)

This is an introductory graduate level course in financial economics, intended for students with strong technical backgrounds who are comfortable with mathematical arguments. The course is divided into three main parts: deterministic finance, singleperiod uncertainty finance and options theory and its applications. Prerequisite: GBUS 420.

ECO 424. Advanced Numerical Methods (3)

This course focuses on techniques that apply directly to economic analysis. A particular emphasis is on problems in finance. The course teaches students how to use EXCEL macros and advanced VBA (the industry standard). It is designed for decisionmaking in business settings.

ECO 425. CostBenefit Analysis (3)

Theory and methods of costbenefit analysis; efficiency and equity as criteria in program evaluation; proper measurement of market and nonmarket costs and benefits; consideration of risk, uncertainty, appropriate discounting techniques and distributional consequences; applications include the evaluation of health care policies and therapies. Prerequisites: ECO 401 and ECO 402 or equivalent; ECO 357 or 415; statistical software beyond Excel; or instructor permission.

ECO 428. (GBUS 428) Capital and Interest Theory (3)

Theories of interest and capital. Annuities; applications of present value theory; investment valuation under uncertainty and risk; term structure of interest rates; the theory of savings, cost of capital, and capital formation. Prerequisite: MBA 402 or equivalent.

ECO 429. (GBUS 429) Monetary Theory (3)

The role of money in the economy from theoretical and empirical perspectives. The influence of money and prices, interest rates, output, and employment.

ECO 430. (GBUS 430) Public Finance (3)

The economics of public spending and taxation; principles of government debt management; theories of budgeting and costbenefit analysis and public choice.

ECO 436. Economic History of the United States (3)

Analysis of the colonial economy, transition to industrialization, and the role of trade and transportation in America's development. A consideration of the importance of slavery to the 19thcentury American economy and other New World economies. Origin and development of banking and financial markets. Prerequisites: ECO 401 and ECO 402 or equivalents.

ECO 440. Labor Economics (3)

The economics of labor markets and various labormarket institutions with emphasis on current theoretical and empirical research. Prerequisites: ECO 401 and ECO 402 or equivalents.

ECO 447. Economic Analysis of Market Competition (3)

Mathematical models based on game theory and industrial organization. Cases are used to analyze the strategic interaction of firms and governments as competitors and partners. Prerequisites: ECO 401 and ECO 402 or equivalent; 2 semesters calculus; or instructor permission.

ECO 451. Urban Economics (3)

The application of traditional and spatial economics to the location of economic activity focusing on the urban economic problems of business location, housing, land value, land use, and intraurban transportation.

ECO 453. Government Regulation of Business (3)

Analysis of the economic justification for government regulation of private enterprise. Topics include antitrust policy, utilities, and health, safety and environmental regulation. Prerequisite: ECO 402 or equivalent.

ECO 454. Economics of Environmental Management (3)

Economic theory of natural resources. Optimal policies for the development of renewable and nonrenewable resources and environmental quality. Prerequisite: ECO 402 or equivalent.

ECO 455. Health Economics (3)

Economic theory of health care delivery systems. Financing health care services. Case studies of specific economicfinancing problems and/or international comparisons of health care delivery. Prerequisite: ECO 401 and ECO 402 or equivalents or permission of the instructor.

ECO 456. Industrial Organization (3)

The goal of the course is to review theoretical and empirical attempts by economists to understand market structures lying between the extremes of perfect competition and monopoly. The course will focus first on describing the current U.S. industrial structure and reviewing models of imperfect competition. The course then shifts to a closer study of individual firm behavior. The final segment of the course is an overview of two significant relationships between government and industry caused by the existence of imperfect competition.

ECO 457. BioPharmaceutical Economics (3)

Characteristics of the market for pharmaceuticals; barriers to entry, competitions and innovation' pricing and regulation; physician prescribing behavior; commercialization and financing of biotech startups; international comparisons of public policy. Prerequisites: ECO 401 and ECO 402 or equivalents or instructor permission.

ECO 460. Time Series Analysis (3)

Classical decomposition of time series, trend analysis, exponential smoothing, spectral analysis and BoxJenkins autoregressive and moving average methods.

ECO 461. Forecasting (3)

Methods of economic and business forecasting.

ECO 462. Advanced Statistics for Business and Economics (3)

An expanded development of statistical concepts necessary for business and economic research. Topics include probability theory, sets, density functions and distributions, sampling distributions, point estimation, moment generating functions, maximum likelihood, classical statistical inference, power functions, likelihood ratio tests, and nonparametric tests. Prerequisite: calculus.

ECO 463 (IE 458). Topics in Game Theory (3)

A mathematical analysis of how people interact in strategic situations. Topics include normalform and extensiveform representations of games, various types of equilibrium requirements, the existence and characterization of equilibria, and mechanism design. The analysis is applied to microeconomic problems including industrial organization, international trade, and finance. Prerequisites: Two semesters of calculus, ECO 414 and ECO 412 , or permission of the instructor.

ECO 472 Special Topics in Economics (13)

Extended Study of an approved topic not covered in scheduled courses. May be repeated for credit.

ECO 471. International Economic Development (3)

An introduction to the basic theoretical concepts in international economic development and an evaluation of their application by means of a representative sample of the literature.

ECO 472. International Trade Theory (3)

Theories of comparative advantage, factor price equalization, trade and welfare, tariffs, trade and factor movements. Prerequisite: ECO 413 or consent of the chair.

ECO 473. International Monetary Economics (3)

Theory of the balance of payments, the microeconomics of international finance, various approaches to balanceofpayments adjustments, theories of foreign exchangerate determination, and macroeconomic policy under fixed and flexible exchange rates. Prerequisite: ECO 417 or consent of the chair.

ECO 475. Special Topics in Economics (1-3)

Extended study of an approved topic not covered in scheduled courses. May be repeated for credit.

ECO 480. Economics of Technological Change (3)

Explores theoretical models and empirical evidence on the economics of innovation and technical change. Includes examination of: the role of technology in competitiveness, industrial structure, and economic growth; alternative models of the innovative process; incentives for and other conditions affecting research and development; the evaluation of the justifications for government support of R&D. Prerequisite: ECO 402 or equivalent.

ECO 490 Master's Thesis ECO 499 Dissertation